Retinal Detachment Clinical Trial
Official title:
Changes of Macular Pigment Optical Density and Parameters After Nd: YAG Laser Posterior Capsulotomy in Cases With Posterior Capsule Opacification
Verified date | July 2019 |
Source | Afyon Kocatepe University Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
It has been hypothesized that potential effects of laser Nd: YAG laser posterior capsulotomy may affect macular pigment as well as choroidal thickness, macular thickness and anterior chamber parameters, so it was aimed to investigate possible effects of Nd: YAG laser posterior capsulotomy on macular pigment optical density, choroidal thickness, macular thickness and anterior chamber parameters in cases with posterior capsule opacification in this study.
Status | Completed |
Enrollment | 38 |
Est. completion date | May 16, 2016 |
Est. primary completion date | April 12, 2016 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 45 Years to 65 Years |
Eligibility |
Inclusion Criteria: - Best-corrected visual acuity (BCVA) logMAR <0.3 - Duration at least 2 years after cataract surgery - Between the ages of 45 and 65 years (45=age=65) Exclusion Criteria: - Corneal scarring, diffuse posterior PCO or intravitreal hemorrhage that prevents appearance of the fundus - Occluded angle by gonioscopy (grade 0, narrow angle, grade I, grade II) - Presence of macular or peripheral retinal pathologies or choroidopathy - High risk for RD - Presence of macular edema in the macular area - Detection of macular fluid or edema in OCT - Active intraocular inflammation - Previous laser PRP, Nd: YAG laser posterior capsulotomy, laser iridotomy or selective laser trabeculoplasty interventions - Previous iridectomy, glaucoma or vitreoretinal surgery - Glass intraocular lens - Spherical refractive error = ±6.00 D or cylinder refractive error = ±3.00 D - Inadequate stability of the eye - Systemic diseases that may affect the choroidal blood flow such as cardiological diseases - Current use of carotenoid supplementation - Changing eating habits - Gastrointestinal diseases that could cause disturbance of dietary absorption |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Afyon Kocatepe University Hospital |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Changes of Foveal and Pericentral Pigment Optical Density (Log Unit) From Baseline at 2 Months | Foveal and pericentral pigment optical density was measured by using color perimetry technique and recorded as log unit before Nd: YAG laser posterior capsulotomy, at 1 week, 1 month and 2 months | 2 months | |
Primary | Changes of Subfoveal, Temporal and Nasal Choroidal Thicknesses (Micrometer) From Baseline at 2 Months | Subfoveal, temporal and nasal choroidal thicknesses were measured by using enhanced-deep imaging optical coherence tomography and recorded as micrometer before Nd: YAG laser posterior capsulotomy, at 1 week, at 1-month and at 2-month | 2 months | |
Primary | Changes of Anterior Chamber Depth (Millimeter) From Baseline at 2 Months | Anterior chamber depth was measured by using anterior segment module optical coherence tomography and recorded as millimeter before Nd: YAG laser posterior capsulotomy, at 1 week, at 1-month and at 2-month | 2 months | |
Primary | Changes of Iridocorneal Angle From Baseline at 2 Months | Iridocorneal angle was measured by using anterior segment module optical coherence tomography and recorded as millimeter before Nd: YAG laser posterior capsulotomy, at 1 week, at 1-month and 2-month | 2 months | |
Secondary | Changes of Central Macular Thicknesses (Micrometer) From Baseline at 2 Months | 2 Months |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03332758 -
Inflammasomes in Cell Death in FTMH, ERM, and RRD
|
||
Completed |
NCT03660384 -
Silicone Oil Versus Gas in PDR Patients Undergoing Vitrectomy
|
N/A | |
Recruiting |
NCT03713268 -
Intraoperative OCT Guidance of Intraocular Surgery II
|
||
Completed |
NCT04535622 -
Efficacy of Exercise Program for Facedown Posture-related Pain After Retinal Surgery
|
N/A | |
Recruiting |
NCT05863312 -
REtinal Detachment Outcomes Study
|
N/A | |
Recruiting |
NCT05561569 -
Air Versus Gas Tamponade in Primary Retinal Detachment
|
N/A | |
Not yet recruiting |
NCT05538156 -
Internal Limiting Membrane Peeling in Retinal Detachment Surgery
|
N/A | |
Completed |
NCT03046719 -
Subconjunctiva Bupivacaine as Analgesia in Intravitreal Silicone Oil Removal
|
N/A | |
Recruiting |
NCT01261533 -
Flexibility, Efficacy, and Safety of a Foldable Capsular Vitreous Body in the Treatment of Severe Retinal Detachment
|
Phase 1 | |
Terminated |
NCT02068625 -
Rasagiline (Azilect) - Neuroprotection for Macula-off Retinal Detachment
|
Phase 4 | |
Completed |
NCT00000140 -
The Silicone Study
|
Phase 3 | |
Recruiting |
NCT05543018 -
Effect of Intraocular Tamponade on Visual Perception
|
N/A | |
Not yet recruiting |
NCT04518696 -
Suprachoroidal Buckling for the Management of Rhegmatogenous Retinal Detachment
|
N/A | |
Completed |
NCT06166914 -
Efficacy of 5-fluorouracil and Low Molecular Weight Heparin in High-risk Pediatric Retinal Detachment
|
N/A | |
Enrolling by invitation |
NCT05566626 -
Retinal Oxygenation Estimation Trial With Mantis Photonics Hyperspectral Camera
|
N/A | |
Not yet recruiting |
NCT03631108 -
Feasibility Study and Preliminary Application Study on Iris OCTA
|
||
Recruiting |
NCT02201706 -
Multi-electrocoagulation Retinectomy for Retinal Re-detachment in Silicone Oil Filled Eye
|
N/A | |
Completed |
NCT03218371 -
Scleral Self-indentation Chandelier-assisted Peripheral Vitrectomy Under Air Rhegmatogenous Retinal Detachment.
|
N/A | |
Completed |
NCT00000154 -
Diabetic Retinopathy Vitrectomy Study (DRVS)
|
Phase 3 | |
Recruiting |
NCT05583253 -
Visual Outcome of Vitrectomy After Refractive Surgery
|
N/A |