Clinical Trials Logo

Respiratory Physiology clinical trials

View clinical trials related to Respiratory Physiology.

Filter by:
  • None
  • Page 1

NCT ID: NCT04649957 Completed - Clinical trials for Infections, Respiratory

Profiling Recovery of Those Discharged Into the Community With COVID-19

Start date: August 1, 2021
Phase:
Study type: Observational

Currently, there are few studies that have been established that consist of a variety of established and coherent approaches that sought to profile the determinants of recovery, nor used interrogative procedures to understand lasting physical impairment. In this context, measurements obtained from an assessment of cardio-respiratory responses to physiological stress could provide an important insight regarding the integrity of the pulmonary-vascular interface and characterisation of any impairment or abnormal cardio-respiratory function [4]. Indeed, current approaches are being developed to support patients using previous knowledge from other acute respiratory infections (e.g. Acute Respiratory Distress Syndrome; ARDS and Middle Eastern Respiratory Syndrome; MERS), approaches that do not consider the novel challenges presented by COVID-19. The knowledge obtained from the proposed research plan will inform the development of COVID-19 specific rehabilitation and clinical management guidelines which can be implemented globally to increase patient wellbeing, physical capacity, and functional status which will be directly related national and international health and wellbeing, economical and societal impacts.

NCT ID: NCT04424277 Completed - Clinical trials for Respiratory Physiology

Deformation of the Diaphragm Zone of Apposition

ZADSPECTRA
Start date: March 14, 2019
Phase:
Study type: Observational

The assessment of the work of the respiratory muscles is a fundamental clinical data in intensive care, especially to guide the management of patients requiring ventilatory support. This data is difficult to access in current practice. The reference technique to estimate the work of breathing (transdiaphragmatic pressure) is not feasible in clinical routine and evaluates only the respiratory work of the diaphragm, not that of the accessory muscles. The ultrasound technique of speckle tracking allows a fine and multidimensional analysis of the deformation of the respiratory muscles during the respiratory cycle. The investigators hypothesize that the analysis of the multidimensional deformation of the diaphragm at the level of the apposition zone can produce a robust and reproducible index, which is correlated with the work of breathing. The performance of this index will be compared to that of the thickening fraction of the diaphragm. On the other hand, the investigators will evaluate the feasibility of measuring the thickening of the accessory respiratory muscles (scalene and intercostal).

NCT ID: NCT03463096 Completed - Clinical trials for Respiratory Physiology

Advanced Gravitational Physiology the Lung Under High-G Acceleration

Start date: February 20, 2018
Phase: N/A
Study type: Interventional

This is a study of advanced lung physiology in altered gravitational conditions, consisting of respiratory measurements in healthy volunteers during high G acceleration on a long-arm human centrifuge.

NCT ID: NCT02957045 Completed - Clinical trials for Respiratory Physiology

Alternative Measurements of Cough Pressure and Effects of Epidural Anaesthesia on Cough Pressure

ESPIRATOS
Start date: August 2005
Phase: N/A
Study type: Interventional

Pressure generated by cough is an expression of expiratory muscle strength. Cough pressure (Pcough) is usually measured with gastric and/or esophageal catheters, but these are often either inconvenient or uncomfortable for the patient. The aim of this study was to evaluate whether central venous, vesical or rectal catheters could be useful to measure cough pressures as alternative sites to standard esophageal and gastric balloons.

NCT ID: NCT00785447 Completed - Clinical trials for Cardiopulmonary Resuscitation

Comparison of the Efficiency of Mouth-to-nose Breathing With Mouth-to-mouth Breathing

Start date: March 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to find out the best way of providing artificial breathing during cardiopulmonary resuscitation (CPR). Current standard CPR involves giving mouth-to-mouth breathing to people requiring CPR. The rescuer pinches the person's nostrils closed and breathes into the mouth of the unconscious person with his or her own mouth. Some CPR studies have shown that it might be easier and more effective to breathe air into a person's nose instead of the mouth. People receiving CPR often have blocked airways, so breathing into the mouth does not always work. We think mouth-to-nose breathing may be more efficient and easier to do. In this case, the rescuer closes the person's mouth by pushing the jaw up and holding it still. Then the rescuer breathes into the unconscious person's nose by covering the nose entirely with his or her mouth. We are doing this study to try to find out which way works better. We will perform both ways of breathing on people who are unconscious (asleep) before planned (non-emergency) surgery and compare their effectiveness.

NCT ID: NCT00784004 Completed - Clinical trials for Respiratory Insufficiency

Investigation of Efficiency of Breathing With Different Breathing Patterns

Start date: November 2007
Phase: N/A
Study type: Interventional

Our aim in this study is to investigate the efficiency of the breathing with different breathing patterns. Ten volunteers and twenty patients having respiratory problems will be coached on their breathing through specific masks which will provide four different breathing patterns. These patterns will be 1) Breathing in through the nose only and out through the mouth only 2) Breathing in through the mouth only and out through the nose only 3) Breathing in and out through the nose only 4) Breathing in and out through the mouth only The data obtained from volunteers and patients will be compared within and between the groups.