Acute Viral Respiratory Infections in Elderly

Respiratory Infections, Acute Clinical Trial

Official title:

Etiology and Impact of Acute Viral Respiratory Infections in Ambulatory Elderly Populations

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT00170495
• Other study ID #: 04-049
• Secondary ID: H-14802
• Status: Terminated
• Phase: N/A
• First received: September 12, 2005
• Last updated: August 26, 2010
• Start date: September 2004
• Est. completion date: July 2006

Study information

• Verified date: September 2008
• Source: National Institute of Allergy and Infectious Diseases (NIAID)
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Federal Government
• Study type: Observational

Clinical Trial Summary

This study is designed to assess the causes and impact of acute respiratory illness (common colds, flu, bronchitis, pneumonia) in adults age 65 and older. One of the ways to determine the virus causing a particular illness is to get a blood specimen when a person is sick and again later and look for the body's specific responses that identify the virus. Approximately 3000 subjects will be evaluated and their medical records assessed for details of recent illness and general health to help in understanding the subjects' current illness.

Description:

The purpose of this study is to determine the role of respiratory viruses in the etiology of medically attended acute respiratory illness in elderly populations and to assess the impact of these illnesses. Ambulatory elders presenting for health care with an acute respiratory illness will be recruited. Nose and throat swab specimens will be collected to test for one of the respiratory viruses, and acute and convalescent blood specimens will be collected to test for increases in specific antibody. Specimens will be collected within seven days of the onset of illness and then 1 month later for comparison specimens. A brief questionnaire will accompany the specimens, and more complete data on the illness and consequences will be obtained from the medical record. The pattern of illnesses by virus and their severity and duration will be determined.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 3000
• Est. completion date: July 2006
• Est. primary completion date: July 2006
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 65 Years and older

Eligibility

Inclusion Criteria:

1. 65 years of age or older

2. Presentation to the geriatric clinic with an acute respiratory illness of less than 7 days' duration.

Exclusion Criteria:

1. Presentation to the geriatric clinic with a history of a respiratory illness of greater than 7 days' duration.

2. Physician/physician assistant judgment that the respiratory complaints do not represent an acute infection.

3. Patient declines to permit specimen collection.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Infection
• Respiratory Infections, Acute
• Respiratory Tract Infections

Locations

Country	Name	City	State
United States	Baylor College of Medicine	Houston	Texas

Sponsors (1)

Lead Sponsor	Collaborator
National Institute of Allergy and Infectious Diseases (NIAID)

Country where clinical trial is conducted

United States,