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Cuff Leak Test and Airway Obstruction in Mechanically Ventilated ICU Patients — COSMIC  

Respiratory Failure Clinical Trial

Official title:
Cuff Leak Test and Airway Obstruction in Mechanically Ventilated ICU Patients (COSMIC): A Pilot Randomized Controlled Trial

Clinical Trial Summary

The COSMIC trial will be a multicentred, national, parallel-group, pragmatic vanguard pilot trial.

Clinical Trial Description

The COSMIC trial will be a multicentred, national, parallel-group, pragmatic vanguard pilot trial in adults (≥18 years) who are mechanically ventilated in the ICU with risk factors for LE and an order to extubate has been provided by the treating physician. The aims of this study are to assess: 1. Protocol adherence 2. Recruitment rates 3. Secondary clinical outcomes will be collected, and if feasibility criteria are met, ultimately used in the powered trial pending no major protocol adjustments (otherwise will be reported as cohort data). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05456542
Study type Interventional
Source St. Joseph's Healthcare Hamilton
Contact Jose Estrada
Phone 905-522-1155
Email jestrada@stjosham.on.ca
Status Recruiting
Phase Phase 3
Start date April 5, 2023
Completion date November 30, 2024
View Details
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