Respiratory Failure Clinical Trial
Official title:
Esophageal Balloon Calibration During Assisted Ventilation Modes and Sigh: a Feasibility Study
Esophageal balloon calibration (EBC) has been proposed during controlled mechanical ventilation in intubated patients in order to optimize esophageal pressure (Pes) signal. Actually, at our knowledge, no data exist about EBC during assisted ventilatory modes such as Pressure Support Ventilation (PSV). The primary endpoint of the present investigation is to assess the feasibility of EBC during PSV and PSV plus Sigh.
Assisted ventilatory modes, nowadays, have been proved to reduce complications related to
controlled mechanical ventilation. With these modes, ventilatory cycling is under the
patient's control to an extent depending on the type of ventilatory modality.
Sigh improves oxygenation and lung mechanics during pressure control ventilation and pressure
support ventilation (PSV) in patients with acute respiratory distress syndrome.
In order to better quantify the effects of both PSV and PSV plus Sigh on respiratory
mechanics, the esophageal pressure monitoring could be helpful. However, esophageal pressure
(Pes) assessment requires esophageal ballon calibration (EBC) as demonstrated in intubated
patients under controlled mechanical ventilation.
At our knowledge, no data exist about EBC during assisted ventilatory modes. The primary aim
of the present study is to evaluate the effects of PSV and PSV plus Sigh ventilation on
esophageal balloon best volume in patients admitted to the intensive care unit for acute
respiratory failure.
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