Mechanical Ventilation in the Emergency Department: A Prospective Cross-Sectional Study

Respiratory Failure Clinical Trial

Official title:

Mechanical Ventilation in the Emergency Department: A Prospective Cross-Sectional Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01628523
• Other study ID #: 201205165
• Status: Completed
• Start date: July 2012
• Est. completion date: March 2014

Study information

• Verified date: March 2020
• Source: Washington University School of Medicine
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Despite its life-saving potential, the mechanical ventilator has great potential to do harm. Despite years of research, the mortality in acute lung injury (ALI) remains very high. Treatment options after ALI onset are very limited, therefore prevention may be the best option. Unfortunately, the emergency department has not been studied with respect to mechanical ventilation practices, and its contribution to ALI is unknown. The investigators hypothesize that mechanical ventilation is frequently used in the ED and for a variety of reasons, and that ED mechanical ventilation has an effect on long term outcomes.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 219
• Est. completion date: March 2014
• Est. primary completion date: August 2013
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Ventilation either via an endotracheal tube or tracheostomy

Exclusion Criteria:

• Non-invasive positive pressure ventilation;

• Death in the immediate post-intubation phase of care;

• Chronic ventilator-dependence, either at home or extended care facility.

Related Conditions & MeSH terms

• Acute Lung Injury
• Emergencies
• Lung Injury
• Mechanical Ventilation
• Respiratory Distress Syndrome, Adult
• Respiratory Failure
• Respiratory Insufficiency

Intervention

Other:
• For inclusion in the study, patients will have to require mechanical ventilation either via an endotracheal tube or tracheostomy tube.
Mechanical ventilation via an endotracheal tube or tracheostomy tube

Locations

Country	Name	City	State
United States	University of Cincinnati College of Medicine	Cincinnati	Ohio
United States	University of Iowa College of Medicine	Iowa City	Iowa
United States	Christiana Care Health System	Newark	Delaware
United States	Washington University School of Medicine	Saint Louis	Missouri

Sponsors (4)

Lead Sponsor	Collaborator
Washington University School of Medicine	Christiana Care Health Services, University of Cincinnati, University of Iowa

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	To Further Characterize ED Mechanical Ventilation	In a prospective cross-sectional study design, we will enroll all patients receiving mechanical ventilation in the ED over a one-month time frame.	1 month
Secondary	The Incidence of ARDS in Mechanically Ventilated Emergency Department Patients, and Risk Factors Associated With Progression to ARDS	Development of ARDS after admission to the hospital	1 month