Pathophysiologic Changes in the Respiratory System During Therapeutic Interventions

Respiratory Failure Clinical Trial

Official title:

Pathophysiologic Changes in the Respiratory System During Therapeutic Interventions

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01239433
• Other study ID #: REK S-O, Ref 2010/1340, part B
• Status: Completed
• Phase: N/A
• First received: November 10, 2010
• Last updated: September 26, 2016
• Start date: May 2011
• Est. completion date: May 2016

Study information

• Verified date: September 2016
• Source: Oslo University Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: Norway: Regional Ethics Commitee
• Study type: Observational

Clinical Trial Summary

Airway pressures change during fiberoptic bronchoscopy and endotracheal suctioning. In this study pressure changes are examined in a mechanical lung model and in a population of ICU patients on mechanical ventilation.

Description:

Airway pressures change during fiberoptic bronchoscopy and endotracheal suctioning. In this study such pressure changes are examined in a mechanical lung model and in a population of ICU patients on mechanical ventilation. A systematic recording of airway pressures, tidal volumes and blood gases are carried out during ordinary therapeutic procedures requested by the staff physician. No additional study interventions are carried out.

The aim of the project is to examine negative effects of pressure/volume changes.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 25
• Est. completion date: May 2016
• Est. primary completion date: May 2016
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• > 18 years of age

• on mechanical ventilation

• daily endotracheal suctioning performed

Exclusion Criteria:

• < 18 years of age

• non-invasive ventilation

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

• Respiratory Failure
• Respiratory Insufficiency

Locations

Country	Name	City	State
Norway	Oslo University Hospital - Ulleval	Oslo

Sponsors (1)

Lead Sponsor	Collaborator
Oslo University Hospital

Country where clinical trial is conducted

Norway, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Intrabronchial airway pressure		2013	No