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NCT00840723 Clinical Trial

Bronchoscopy Assisted Sampling of Cells and Fluid From the Lower Respiratory Tract of Human Subjects

Respiratory Diseases Clinical Trial

— SCCOR Bronch  

Official title:
Bronchoscopy-Assisted Sampling of Cells and Fluid From the Lower Respiratory Tract of Human Subjects

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00840723
Other study ID # CTRC 2799
Secondary ID NHLBI P50-HL0849
Status Completed
Phase N/A
First received February 6, 2009
Last updated September 3, 2013
Start date February 2009
Est. completion date August 2013

Study information
Verified date September 2013
Source University of North Carolina, Chapel Hill
Contact n/a
Is FDA regulated No
Health authority United States: Federal GovernmentUnited States: Institutional Review Board
Study type Observational

Clinical Trial Summary

The purpose of this research study is to collect cells and liquid from the air passages of healthy adults, both smokers and non-smokers. These samples will be used for test-tube studies to explore mechanisms of diseases of the respiratory tract, and to compare the samples between people who smoke cigarettes and people who don't. Obtaining these samples requires an invasive procedure called "bronchoscopy".

Recruitment information / eligibility
Status Completed
Enrollment 30
Est. completion date August 2013
Est. primary completion date August 2013
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 18 Years to 75 Years
Eligibility Inclusion Criteria:

- Current cigarette smokers

- Must be otherwise healthy with no chronic illness

Exclusion Criteria:

- Asthma

- Smoking related lung disease (including bronchitis)

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Locations
Country Name City State
United States UNC Center for Environmental Medicine, Asthma and Lung Biology Chapel Hill North Carolina

Sponsors (1)
Lead Sponsor Collaborator
University of North Carolina, Chapel Hill

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary The goal of this project is to define the effect of smoking on key aspects of airway biology. These studies will also provide crucial & novel definition of airway biology in smokers against which COPD & CF patients will be compared. At the time of bronchoscopy No
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