Repeated Implantation Failure Clinical Trial
Official title:
The Study of the Relationship Between TWEAK/Fn14, JAK/STAT3 and IDO in the Immune Microenvironment of Endometrium in Repeated Implantation Failure
The purpose of this study is to find out the possible relationship among TWEAK/Fn14,
JAK/STAT3 and IDO as well as their roles in the dysfunction of immune micro-environment of
endometrium in people diagnosed as repeated implantation failure after in vitro
Fertilization-embryo transfer(IVF-ET).
We will use the technology of Western-blot and Immunohistochemistry to find out the
relationship of the expression of TWEAK/Fn14, JAK/STAT3 and IDO in endometrium . Also, we
will use technology of Western-blot and Immunohistochemistry to determine whether there are
differences of the the expression of TWEAK/Fn14, JAK/STAT3 and IDO in endometrium between
RIF group and control group.
The purpose of this study is to find out the possible relationship among TWEAK/Fn14,
JAK/STAT3 and IDO as well as their roles in the dysfunction of immune micro-environment of
endometrium in people diagnosed as repeated implantation failure after in vitro
Fertilization-embryo transfer(IVF-ET).
We will use the technology of Western-blot and Immunohistochemistry to find out the
relationship of the expression of TWEAK/Fn14, JAK/STAT3 and IDO in endometrium . Also, we
will use technology of Western-blot and Immunohistochemistry to determine whether there are
differences of the the expression of TWEAK/Fn14, JAK/STAT3 and IDO in endometrium between
RIF group and control group.
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Time Perspective: Cross-Sectional
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