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Atosiban Improves Implantation and Pregnancy Rates in Patients With Repeated Implantation Failure

Repeated Implantation Failure Clinical Trial

Official title:
Atosiban Improves Implantation and Pregnancy Rates in Patients With Repeated Implantation Failure

Clinical Trial Summary

Atosiban, administered at embryo transfer, can improve the implantation rate and the clinical pregnancy rate in patients with repeated implantation failure undergoing IVF-ET (in-vitro fertilization and embryo transfer).

Clinical Trial Description

Atosiban is a mixed oxytocin and vasopressin V1A receptor antagonist.Combined antagonism at oxytocin and vasopressin V1A receptors reduces uterine contractions with a corresponding decrease in intrauterine production of prostaglandin F2alpha and improved uterine blood supply. These effects are of potential benefit for implantation support during IVF-ET cycles. ;

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01493440
Study type Interventional
Source An Sinh Hospital
Contact
Status Completed
Phase N/A
Start date March 2011
Completion date September 2011
View Details
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