Renal Transplantation Clinical Trial
Official title:
Comparison Thymoglobulin® Versus Grafalon® in Renal Transplantation - Spiesser Group (Retro/Prospective Study) I
This is a prospective, multicenter, observational, non -interventional study with comparison
with an historical cohort Investigators will compare the efficacy and safety of Thymoglobulin
(Sanofi-Aventis) versus Grafalon (Neovii, previously ATG-Fresenius) in renal transplantation
by evaluating patient survival, graft survival, delayed graft function, acute rejection, DSA
occurrence and toxicities, various infections including CMV and BK virus incidence, MACE
(major cardiac adverse event) and cancer.
Investigators will also compare cumulative treatment and follow up costs and other key
criteria available in the ASTRE database.
This is a prospective, multicenter, observational, non -interventional study with comparison
with an historical cohort Investigators will compare the efficacy and safety of Thymoglobulin
(Sanofi-Aventis) versus Grafalon (Neovii, previously ATG-Fresenius) in renal transplantation
by evaluating patient survival, graft survival, delayed graft function, acute rejection, DSA
occurrence and toxicities, various infections including CMV and BK virus incidence, MACE
(major cardiac adverse event) and cancer.
Investigators will also compare cumulative treatment and follow up costs and other key
criteria available in the ASTRE database.
Justification for a non-interventional study: in the study the medicinal products will be
prescribed in the usual manner in accordance with the terms of the marketing authorisation.
The assignment of the patient to the product is not decided in advance by a trial protocol
but falls within current practice of the centre and the prescription of the medicine is
clearly separated from the decision to include the patient in the study. No additional
diagnostic or monitoring procedures are applied to the patients and epidemiological methods
are used for the analysis of collected data.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Not yet recruiting |
NCT06026592 -
Detection of Plasma DNA of Renal Origin in Kidney Transplant Patients
|
||
| Active, not recruiting |
NCT02444429 -
3-month Screening Biopsy to Optimize the Immunosuppression in Renal Transplantation
|
Phase 3 | |
| Completed |
NCT02238418 -
Efficacy of Usual Vitamin D Supplementation and Its Impact on Children and Adolescents Calciuria.
|
Phase 4 | |
| Completed |
NCT01729494 -
Belatacept Early Steroid Withdrawal Trial
|
Phase 4 | |
| Terminated |
NCT01436305 -
Optimization of NULOJIX® Usage As A Means of Avoiding CNI and Steroids in Renal Transplantation
|
Phase 2 | |
| Terminated |
NCT01276834 -
Comparison of Immunosuppression on Progression of Arteriosclerosis in Renal Transplantation
|
Phase 4 | |
| Completed |
NCT02843295 -
Catalytic Antibodies to Predict Uninvasively Late Transplant Failure
|
N/A | |
| Completed |
NCT00842699 -
Characterization of Immunological Profile of Renal Transplant Patients Undergoing Induction Treatment With Thymoglobulin vs. IL-2 Receptor Antagonist Basiliximab
|
N/A | |
| Completed |
NCT00525681 -
Interaction Between Rimonabant and Cyclosporine and Tacrolimus
|
Phase 4 | |
| Completed |
NCT00776750 -
Influenza Vaccination in Hemodialysis Patients and Renal Transplant Recipients
|
Phase 4 | |
| Completed |
NCT00189735 -
A Study to Evaluate FK778 in Kidney Transplant Patients
|
Phase 2 | |
| Recruiting |
NCT04052867 -
Intravenous Lignocaine Infusion in Laparoscopic Donor Nephrectomy
|
N/A | |
| Recruiting |
NCT03114826 -
Study of the Impact of VEGF Polymorphism on the Development of Renal Carcinoma in Renal Transplant Patients
|
N/A | |
| Completed |
NCT02587052 -
A 1-year Comparison of Generic Tacrolimus (Tacni) and Prograf in Renal Transplant Patients - a Retrospective Matched Pair Analysis, GenTac
|
||
| Completed |
NCT02020642 -
Effect of Renal Transplantation on Obstructive Sleep Apnea in End Stage Renal Disease Patients (SASinTx)
|
N/A | |
| Completed |
NCT01435291 -
AADAPT - Analysis of Advagraf Dose Adaptation Post Transplantation
|
Phase 4 | |
| Recruiting |
NCT01001065 -
Association of the Intrarenal Resistance Index (RI) of Transplanted Kidneys With Generalized Atherosclerosis
|
N/A | |
| Completed |
NCT00978965 -
Identification of Patients With High Probability of Poorly Responding to Therapy With Mycophenolic Acid Prodrugs
|
||
| Recruiting |
NCT00903188 -
Calcineurin Inhibitor (CNI) Versus Steroid Cessation in Renal Transplantation
|
Phase 4 | |
| Completed |
NCT00419575 -
Renal Transplantation With Immune Monitoring
|
N/A |