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Renal Insufficiency, Chronic clinical trials

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NCT ID: NCT00267514 Completed - Clinical trials for Chronic Kidney Disease

Study to Demonstrate Equivalence of Sevelamer Carbonate Powder and Sevelamer HCl Tablets in Haemodialysis Patients

Start date: January 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if sevelamer carbonate powder is an effective treatment for the control of serum phosphorous levels in patients on dialysis when compared to sevelamer hydrochloride tablets.

NCT ID: NCT00257920 Completed - Clinical trials for Secondary Hyperparathyroidism

A Study of Zemplar® Injection and Hectorol® Injection on Intestinal Absorption of Calcium in Chronic Kidney Disease

Start date: June 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the effects of Zemplar® Injection and Hectorol® Injection on intestinal calcium absorption in Chronic Kidney Disease Stage 5 subjects on hemodialysis.

NCT ID: NCT00255437 Completed - Anemia Clinical Trials

Ferumoxytol Versus Oral Iron in the Treatment of Anemia in Non-Dialysis Dependent Chronic Kidney Disease Patients

Start date: June 2004
Phase: Phase 3
Study type: Interventional

The study will evaluate the safety and efficacy of a new intravenously administered iron drug to treat anemia in patients with chronic kidney disease who are not on dialysis.

NCT ID: NCT00255424 Completed - Anemia Clinical Trials

Ferumoxytol Versus Oral Iron in the Treatment of Anemia in Non-Dialysis Dependent Chronic Kidney Disease Patients

Start date: May 2004
Phase: Phase 3
Study type: Interventional

The study will evaluate the safety and efficacy of a new intravenously administered iron drug to treat anemia in patients with chronic kidney disease who are not on dialysis.

NCT ID: NCT00242164 Completed - Clinical trials for Chronic Kidney Disease

Defining The Role Of Dialysate Magnesium In Arrhythmogenicity On Dialysis

Start date: November 2005
Phase: Phase 2
Study type: Interventional

The study is being performed to better understand dialysis techniques which keep heart functions stable during dialysis. People on dialysis have a high risk for heart disease and strokes. More information about dialysis techniques that keep hearts stable may help prevent the high risk of cardiovascular disease and death and help to reduce discomfort during dialysis. This study will look at the way that the magnesium in dialysate affects heart function during dialysis. High or low levels of magnesium may change the way hearts beat. The question asked is if lowering the amount of magnesium in dialysate will affect the amount of magnesium in blood or change the heart beat.

NCT ID: NCT00239642 Completed - Anemia Clinical Trials

Safety and Efficacy of Iron Sucrose in Children

Start date: July 2005
Phase: Phase 4
Study type: Interventional

Comparison of three potential iron sucrose maintenance regimens in pediatric chronic kidney disease (CKD) patients

NCT ID: NCT00234702 Completed - Kidney Diseases Clinical Trials

Efficacy and Safety of Lanthanum Carbonate in Reducing Serum Phosphorus Levels in Subjects With Stage 3 and 4 Chronic Kidney Disease

Start date: January 11, 2006
Phase: Phase 2
Study type: Interventional

Chronic kidney disease (CKD) can result in a loss of ability to filter and excrete phosphate. The body's attempt to adjust to an increased level of phosphate in the blood can result in elevated levels of hormones and minerals resulting in serious clinical consequences. This study is being conducted to evaluate the safety and efficacy of lanthanum carbonate in lowering high levels of phosphorus in the blood in subjects with CKD Stages 3 and 4 compared to placebo.

NCT ID: NCT00234533 Completed - Clinical trials for Renal Insufficiency, Chronic

Study to Define Optimal IGF-1 Monitoring in Children Treated With NutropinAq

OPTIMA
Start date: June 2004
Phase: Phase 3
Study type: Interventional

The main purpose of this study is to establish an optimal monitoring regimen in NutropinAq treated children, using newly developed capillary blood spot IGF-1 measurement technology.

NCT ID: NCT00231803 Completed - Clinical trials for Chronic Kidney Disease

The Canadian Prevention of Renal and Cardiovascular Endpoints Trial

CanPrevent
Start date: April 2005
Phase: N/A
Study type: Interventional

Advanced kidney disease with it's associated heart and blood vessel problems are becoming more frequent. These problems markedly affect length and quality of life and cost a lot to treat. Treatments are known that can prevent development of advanced kidney and heart disease. These treatments are not being optimally applied in the current health system. This study aims to identify people with relatively early stage chronic kidney disease. With the participation of these people, the study will test whether a nurse coordinated clinic involving a medical kidney specialist, applying the known treatments, can reduce or delay the onset of advanced kidney disease and heart and blood vessel problems such as heart attack, stroke and death, to a greater extent than usual care. The study will also address issues of costs associated with care and illness. The nature of the care provided by the health care professionals will be studied to see how best to achieve good health outcomes.

NCT ID: NCT00228449 Completed - Anemia Clinical Trials

Peginesatide for Anemia in Chronic Hemodialysis Patients

Start date: July 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety, pharmacodynamics (PD), and pharmacokinetics (PK) of multiple intravenous doses of peginesatide in participants with chronic kidney disease (CKD) who are on hemodialysis.