Outcome
Type |
Measure |
Description |
Time frame |
Safety issue |
Primary |
Change in Biochemical parameters |
NGAL in urine |
All these parameters will be evaluated at baseline (presurgery), at the end surgery and 24 hours after surgery in both study groups |
|
Primary |
Change in Biochemical parameters |
Cystatin C(mg/L) in plasma |
will be evaluated at baseline (presurgery), at the end surgery and 24 hours after surgery in both study groups |
|
Primary |
Change in Biochemical parameters |
Creatinine(mg/dL) in plasma |
will be evaluated at baseline (presurgery), at the end surgery and 24 hours after surgery in both study groups |
|
Primary |
Change in Biochemical parameters |
sodium(mMol/L) in plasma |
will be evaluated at baseline (presurgery), at the end surgery and 24 hours after surgery in both study groups |
|
Primary |
Change in Biochemical parameters |
potassium(mMol/L) in plasma |
will be evaluated at baseline (presurgery), at the end surgery and 24 hours after surgery in both study groups |
|
Primary |
Change in Biochemical parameters |
Chloride(mMol/L) in plasma |
will be evaluated at baseline (presurgery), at the end surgery and 24 hours after surgery in both study groups |
|
Primary |
Change in Biochemical parameters |
albumin(g/dL) in plasma |
will be evaluated at baseline (presurgery), at the end surgery and 24 hours after surgery in both study groups |
|
Primary |
Change in Biochemical parameters |
osmolarity(mOsm/Kg) in plasma |
will be evaluated at baseline (presurgery), at the end surgery and 24 hours after surgery in both study groups |
|
Primary |
Change in Biochemical parameters |
NGAL in plasma |
will be evaluated at baseline (presurgery), at the end surgery and 24 hours after surgery in both study groups |
|
Primary |
Change in Biochemical parameters |
Creatinine(mg/dL) in urine |
will be evaluated at baseline (presurgery), at the end surgery and 24 hours after surgery in both study groups |
|
Primary |
Change in Biochemical parameters |
sodium(mMol/L) in urine |
will be evaluated at baseline (presurgery), at the end surgery and 24 hours after surgery in both study groups |
|
Primary |
Change in Biochemical parameters |
potassium(mMol/L) in urine |
will be evaluated at baseline (presurgery), at the end surgery and 24 hours after surgery in both study groups |
|
Primary |
Change in Biochemical parameters |
Chloride(mMol/L) in urine |
will be evaluated at baseline (presurgery), at the end surgery and 24 hours after surgery in both study groups |
|
Primary |
Change in Biochemical parameters |
albumin(g/dL) in urine |
will be evaluated at baseline (presurgery), at the end surgery and 24 hours after surgery in both study groups |
|
Primary |
Change in Biochemical parameters |
osmolarity(mOsm/Kg) in urine |
will be evaluated at baseline (presurgery), at the end surgery and 24 hours after surgery in both study groups |
|
Secondary |
Need for postoperative mechanical ventilation |
hours of mechanical ventilation in ICU |
24 hours |
|
Secondary |
ICU length of stay |
hours in ICU |
up to 24 hours |
|
Secondary |
anesthetic recovery |
time to extubation(minutes). |
These variable will be recorded immediately after surgery (from anesthetics discontinuation). The postanesthesia recovery score before will be recorded at baseline and after surgery. time frame upto 1 hour(stimated) |
|
Secondary |
anesthetic recovery |
time to spontaneous eye opening(minutes) |
These variable will be recorded immediately after surgery (from anesthetics discontinuation). The postanesthesia recovery score before will be recorded after surgery. timeframe up to 1 hour(stimated). |
|
Secondary |
anesthetic recovery |
time until first response to verbal commands(minutes) |
These variable will be recorded immediately after surgery (from anesthetics discontinuation). The postanesthesia recovery score before will be recorded after surgery. timeframe up to 1 hour(stimated). |
|
Secondary |
anesthetic recovery |
The post-anesthesia recovery score ( Modified Aldrete score) (0-1-2 from worse to better) |
These variable will be recorded immediately after surgery (from anesthetics discontinuation). The postanesthesia recovery score before will be recorded at baseline and after surgery. timeframe 1 hour(stimated) |
|