Renal Failure Clinical Trial
Official title:
Assessment of the Sympathetic Nervous System Blockade of the Upper Limb After a Brachial Plexus Block in Patients With End Stage Renal Failure
The purpose of this study is to investigate what effect a local anesthetic nerve block of the arm in patients with end stage renal failure has upon blood flow in the skin of the arm.
Aim
To quantify the degree of sympathetic blockade in the upper limb in patients with end stage
renal failure produced during a regional anaesthetic technique, using laser Doppler
flowmetry.
Hypothesis
Regional anaesthesia of the upper limb results in blockade of motor and sensory nerves,
providing surgical and post-operative analgesia. Sympathetic nerves are also blocked
resulting in local vasodilatation. This may be of benefit in surgery where enhanced blood
flow is beneficial such as arterio-venous fistula creation. The degree and duration of
sympathetic blockade produced by regional blocks however, has never been quantified. This
study aims to quantify sympathetic blockade by measuring the changes in skin blood flow and
skin temperature after placement of a brachial plexus block.
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Observational Model: Cohort, Time Perspective: Prospective
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