Clinical Trials Logo
  1. Home
  2. Renal Disease
  3. NCT05529186
  4. Details
NCT05529186 Clinical Trial

Causes of Mortality in Kidney Transplant Recipients

Renal Disease Clinical Trial

— Paradigme  

Official title:
Causes of Mortality in Kidney Transplant Recipients, a Paradigm Shift

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT05529186
Other study ID # 8558
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date March 14, 2022
Est. completion date December 14, 2023

Study information
Verified date November 2023
Source University Hospital, Strasbourg, France
Contact Sophie CAILLARD, MD, PhD
Phone 33 3 69 55 51 20
Email sophie.caillard@chru-strasbourg.fr
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The causes of mortality in kidney transplant patients and the risk factors for mortality have been widely published. However, there is a high variability according to geographical areas and time. Recent studies suggest that the classical hierarchy of causes of mortality, i.e. the predominance of cardiovascular causes of death, could be overturned by the increase in infectious and cancer-related deaths. Investigators will try to highlight this paradigm shift and the related risk factors by studying two large French transplantation databases.

Recruitment information / eligibility
Status Recruiting
Enrollment 7000
Est. completion date December 14, 2023
Est. primary completion date December 14, 2023
Accepts healthy volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion criteria: - Adult subject (=18 years old) during transplantation - Transplantation performed between 01/01/2008 and 31/12/2014 - Kidney transplant subject, double transplants kidney + pancreas, or kidney + islets of Langherans - Subject previously transplanted other organs - Subject not objecting, after being informed, to the reuse of their data for the purposes of this research Exclusion criteria: - Subject who expressed their opposition to participating in the study - Subject having received a double transplant during the same operation: kidney + heart, kidney + liver, kidney + lungs

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
France Service Néphrologie-Dialyse-Transplantation - CHU de Strasbourg - France Strasbourg

Sponsors (1)
Lead Sponsor Collaborator
University Hospital, Strasbourg, France

Country where clinical trial is conducted

France, 

Outcome
Type Measure Description Time frame Safety issue
Primary Distribution of the causes of death of kidney transplant recipients presented in the form of percentage Six months of starting dialysis
See also
  Status Clinical Trial Phase
Active, not recruiting NCT03672110 - Slow and Low Start of a Tacrolimus Once Daily Immunosuppressive Regimen Phase 3
Completed NCT01545531 - Two-Point Measurement of Glomerular Filtration Rate by Iohexol Plasma Disappearance N/A
Recruiting NCT05700903 - Contributions to Hypertension With Androgen Deprivation Therapy Phase 4
Completed NCT03717883 - ADPKD Alterations in Hepatic Transporter Function
Withdrawn NCT04556721 - A Pharmacokinetic Study of Sugammadex in Dialysis Patients Phase 1
Recruiting NCT04078750 - PLATO - Medication Adherence in Transplant Recipients N/A
Not yet recruiting NCT04531124 - Cardiovascular and Renal Outcomes of Integrated Management of Blood Pressure and Other Cardiometabolic Risks in Hypertensives
Completed NCT03107195 - Biokinetics Study of Tc-99m DMSA in Pediatric Molecular Imaging
Completed NCT03463148 - Validation of a Sensor for Non-Invasive Measurements
Recruiting NCT03578523 - Renal MR Feasibility in Renal Disease
Withdrawn NCT01468259 - A Multi-Center, Open-Label Study Phase 1
Completed NCT01256983 - Light for Renal Transplant Recipients Having a Sleep-Wake Dysregulation Phase 0
Completed NCT06070337 - H-Guard Pilot Safety Evaluation in Haemodialysis Patients N/A
Completed NCT05593211 - Assess Safety and Performance of the Kronos Electrocautery Device for Electrocautery Procedures Following Coaxial Biopsy Procedures N/A
Completed NCT03242343 - VasQ External Support for Arteriovenous Fistula N/A
Completed NCT03438123 - Data Collection Study for the Spectrum Dynamics Multi-purpose CZT SPECT Camera N/A
Completed NCT01334333 - Comparison of Medication Adherence Between Once and Twice Daily Tacrolimus in Stable Renal Transplant Recipients Phase 4
Recruiting NCT05443321 - Advancing Health Information Exchange (HIE) During Inter-hospital Transfer (IHT) to Improve Patient Outcomes N/A
Completed NCT04407182 - Safety and Efficacy of Viusid and Asbrip in Hospitalized Patients Infected by SARS-Cov-2 With COVID-19 Phase 2
Not yet recruiting NCT04834089 - Clinical Trial for Assessment of Anti-SARS-CoV-2 Serum for Early Treatment of COVID-19 Cases Phase 1/Phase 2