Efficacy of Magnesium Sulfate on Reducing Renal Colic in the Emergency Department

Renal Colic Clinical Trial

Official title:

Efficacy of Magnesium Sulfate on Reducing Renal Colic in the Emergency Department

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03617289
• Other study ID #: 10080
• Status: Completed
• Phase: N/A
• Start date: January 2016
• Est. completion date: May 2016

Study information

• Verified date: February 2023
• Source: Henry Ford Health System
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

To determine if magnesium sulfate paired with an analgesic medication will improve patient pain from renal colic compared with analgesic alone.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 37
• Est. completion date: May 2016
• Est. primary completion date: May 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 100 Years

Eligibility

Inclusion Criteria:

• Age >18 years old and <100 years old.

• Patients seen in the Emergency Department at Henry Ford Macomb hospital.

• Patients that are A+Ox3.

• Patients who have typical presentation for renal colic.

Exclusion Criteria:

• Age <18 years.

• Patients with a history of dementia, acute delirium or altered mental status.

• Patients with inability to consent to study or inability to fill questionnaire independently.

• Patients with chronic kidney disease and allergies to study drugs.

• Patients that are pregnant (women who are of child-bearing potential will be screened with a urine BHCG).

• Patients with stroke activation or symptoms.

• Patients with trauma activations.

• Patients over the age of 100 years old are excluded as they make up a small percentage of the population and may become identifiable because of their age.

• Imaging study does not show evidence of ureteral stone.

Related Conditions & MeSH terms

• Colic
• Emergencies
• Renal Colic

Intervention

Drug:
• Magnesium Sulfate

• D5W

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Henry Ford Health System

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Pain Score Change	We asked the patient's pain score on a scale of 0-10 with 10 being the highest amount of pain and 0 no pain, before and after treatment (approximately 1 hour). Primary Outcome was the change in score before and after treatment.	1 hour after the completion of treatment medication (Placebo or Study Drug)
Secondary	Percentage of Participants Requiring Opiates for Additional Pain Control	We analyzed how many patients required additional pain control with opiates between the two treatment groups.	Any opiate administration required after re-evaluation of pain score after initial treatment with either placebo or study drug