Renal Colic Clinical Trial
Official title:
Intravenous Magnesium Sulfate Combined to Diclofenac Versus Intravenous Lidocaine Combined to Diclofenac Versus Diclofenac Alone in the ED Treatment of Renal Colic. A Randomized Double Blind Study.
to evaluate the analgesic effect of a standard dose of intravenous magnesium added to intramuscular diclofenac compared to intravenous lidocaine combined to intramuscular diclofenac or intramuscular diclofenac alone in patients presenting to the emergency department with renal colic and whether it can reduce opioid consumption.
Magnesium (MgSO4) is a N-Methyl-D-aspartate (NMDA) receptor antagonist and is thought to be involved in the modulation of pain. There has been little direct evidence that MgSO4 relieve neuropathic pain and prevents opioid-induced hyperalgesia in humans. Intramuscular Diclofenac seems to offer the most effective sustained analgesia for renal colic in the ED and has few side effects. Lidocain became the agent of choice in visceral and central pain. Intravenous lidocain is effective in the management of neuropathic pain such as diabetic neuropathy, post-surgical pain, post herpetic pain, headaches, and neurological malignancies. At low doses, lidocain is known a relatively safe medication. Lidocain seems an effective treatment who can be administrated in the renal colic. Objective of study : The aim of this study is to evaluate the analgesic effect of a standard dose of intravenous magnesium added to intramuscular diclofenac compared to intravenous lidocain combined to intramuscular diclofenac or intramuscular diclofenac alone in patients presenting to the emergency department with renal colic and whether it can reduce opioid consumption. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Withdrawn |
NCT01685658 -
Intravenous Paracetamol Versus Ketoprofen When Treating Renal Colic in Emergency Situations
|
Phase 4 | |
Completed |
NCT01349244 -
Hydronephrosis on Ultrasound With CT Finding in Patients With Renal Colic
|
N/A | |
Recruiting |
NCT04169555 -
"Point of Care" Ultrasound and Renal Colic
|
N/A | |
Completed |
NCT04160520 -
Pramipexole and Morphine for Renal Colic
|
Phase 1/Phase 2 | |
Not yet recruiting |
NCT04080973 -
Metabolic Workup in Patients Suffering From Kidney Stone Disease and Osteopenia
|
N/A | |
Completed |
NCT01979042 -
Urinary Markers for Unilateral Kidney Obstruction
|
N/A | |
Completed |
NCT03865004 -
Combination Trial of Intravenous Paracetamol - Morphine for Treating Acute Renal Colic in Emergency Setting: An Optimum Treatment
|
Phase 4 | |
Completed |
NCT03706404 -
Renal Colic Fast Track Pathway in the Emergency Department.
|
N/A | |
Completed |
NCT03638921 -
35RC17_8826_NEPHROPAIN Phase APRES : Interest of the Equimolar Oxygen Nitride Mixture (MEOPA) in the Treatment of Pain in Patients Presenting to the Emergency Department for Suspected Renal Colic: a Study BEFORE AFTER
|
Phase 2 | |
Completed |
NCT03665753 -
Comparison of IV 10, 20, and 30mg for Renal Colic Pain in the ED
|
Early Phase 1 | |
Not yet recruiting |
NCT05150899 -
Role of Antihistaminic in Acute Renal Colic Prevent Pain Recurrence and Expulsion of Ureteric Stone ≤ 1cm
|
||
Recruiting |
NCT03790514 -
Heat Wrap for Renal Colic
|
N/A | |
Completed |
NCT00646061 -
Pain Control in Renal Colic
|
Phase 1 | |
Completed |
NCT05653401 -
Treatment of Renal Colic in the Emergency Department: Comparison Between Magnesium Sulfate and Lidocaine.
|
Phase 2 | |
Not yet recruiting |
NCT02782273 -
Morphine Versus Ketorolac in Renal Colic
|
Phase 4 | |
Completed |
NCT01352676 -
Limit Computed Tomography (CT) Scanning in Suspected Renal Colic
|
||
Not yet recruiting |
NCT06412900 -
Radiomics and Image Segmentation of Urinary Stones by Artificial Intelligence
|
||
Not yet recruiting |
NCT06342648 -
Intracutaneous Sterile Water and Diclofenac Sodium Injections in Renal Colic
|
N/A | |
Recruiting |
NCT03137498 -
Lidocaine vs Ketorolac for Management of Renal Colic in the Emergency Department
|
Phase 4 | |
Recruiting |
NCT01742689 -
Analgesic Efficacy of Intranasal Desmopressin in Acute Renal Colic
|
Phase 3 |