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A Study of LY2584702 With Erlotinib or Everolimus in Participants With Solid Tumors

Renal Cell Carcinoma Clinical Trial

Official title:
A Phase 1b Trial of LY2584702 in Combination With Erlotinib or Everolimus in Patients With Solid Tumors

Clinical Trial Summary

Study I3G-MC-JGCB (JGCB) is a multicenter, nonrandomized, open-label, dose-escalation Phase 1b study of LY2584702 in combination with either erlotinib or everolimus.

Clinical Trial Description

Study JGCB will consist of the following parts:

Part 1 - Dose Escalation to maximum tolerated dose in each arm.

Arm A - LY2584702 + Erlotinib in participants with advanced or metastatic cancer.

Arm B - LY2584702 + Everolimus in participants with advanced or metastatic cancer.

Part 2 - Dose Confirmation of maximum tolerated dose from each arm in Part 1.

Arm A - LY2584702 + Erlotinib in participants with advanced or metastatic non-small cell lung cancer.

Arm B - LY2584702 + Everolimus in participants with advanced renal cell carcinoma after treatment failure with sunitinib or sorafenib, or advanced neuroendocrine tumors. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01115803
Study type Interventional
Source Eli Lilly and Company
Contact
Status Terminated
Phase Phase 1
Start date March 2010
Completion date June 2011
View Details
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