Anesthesia, Spinal Clinical Trial
Official title:
Determination of Effective Dose 90 of Remimazolam That Can Maintain Loos of Consciousness From Sedation With Remimazolam in Adult Patients
Currently used drugs for monitored general anesthesia include propofol, midazolam, and dexmedetomidine. Each drug has different advantages and disadvantages. Remimazolam causes a relatively small decrease in blood pressure, and it has no injection pain. In addition, remimazolam has a very short onset time, and even after the continuous infusion, the onset of remimazolam is fast, and even after continuous injection, the effect disappeared very quickly due to the short context-sensitive half time. and through continuous infusion, the patient's depth of anesthesia can be maintained constant. In addition, the short duration of action and the ability to quickly reverse the effect of flumazenil suggest that remimazolam can be used effectively under general anesthesia as well as under general anesthesia. Remimazolam can be used as a continuous infusion for general anesthesia. However, it has also been reported to be used for sedation by continuous infusion or divided intravenous infusion. However, the effective infusion dose of remimazolam for supervised general anesthesia without mechanical ventilation has not been established. In this study, the ED90 of the maintenance dose that maintain loss of consciousness in patients when supervised general anesthesia is performed through continuous infusion of remimazolam after spinal anesthesia is obtained.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03324984 -
1% Chloroprocaine(PF) vs. Bupivacaine Spinals
|
Phase 2 | |
Recruiting |
NCT03399019 -
Bispectral Index(BIS) on Depth of Sedation With Dexmedetomidine, Propofol and Midazolam During Spinal Anesthesia
|
N/A | |
Suspended |
NCT03967288 -
Comparison of Clorotekal and Bupivacaine for Short Obstetric Surgery
|
Phase 4 | |
Completed |
NCT03316352 -
Ultrasound-assisted Versus Conventional Landmark-guided Paramedian Spinal Anesthesia in Elderly Patients
|
N/A | |
Completed |
NCT04092478 -
'' Abdominal Crunch Positions With the Others in Terms of Interspinous Distance in Adult Patients ''
|
||
Recruiting |
NCT04128410 -
A Study on Central Transport Characteristics of Flurbiprofen Axetil in Elderly Patients
|
||
Completed |
NCT02961842 -
Combined Colloid Preload And Crystalloid Coload Versus Crystalloid Coload During Spinal Anesthesia for Cesarean Delivery
|
N/A | |
Completed |
NCT04050059 -
Comparison of Two Analgesic Pretreatment Techniques Before Spinal Needle Insertion for Pain Reduction and Maternal Satisfaction Level Assessment in Women Undergoing LSCS.
|
N/A | |
Completed |
NCT02833376 -
Alcohol 70% Versus Chlorhexidine 0.5% in the Spinal Anesthesia Skin Antissepsis
|
N/A | |
Not yet recruiting |
NCT06427382 -
Prediction of Hypotension Using Perfusion Index Following Spinal Anesthesia
|
||
Completed |
NCT03105115 -
Effect of Intrathecal Fentanyl on Spinal Anesthesia During Dexmedetomidine Infusion
|
N/A | |
Terminated |
NCT04996420 -
Goal Directed Fluid Therapy Versus Liberal Fluid Regimen in Primary Elective Hip Artrhoplasty
|
N/A | |
Not yet recruiting |
NCT06418308 -
Intrathecal Dexmedetomidine vs Epinephrine
|
Phase 4 | |
Not yet recruiting |
NCT03142880 -
Spinal Marginally Hyperbaric Ropivacaine for Cesarean Delivery
|
N/A | |
Completed |
NCT03929874 -
Ultrasound Image Study for Ultrasound-assisted Paramedian Spinal Anesthesia
|
||
Completed |
NCT03959644 -
Failure Rate in Spinal Blocks and Determination of Related Factors
|
||
Recruiting |
NCT03497364 -
Combined Spinal-epidural Anesthesia for Cesarean Section Without Prophylactical Prehydration and Vasopressors
|
N/A | |
Completed |
NCT03075488 -
Ultrasound Prescan vs Conventional Landmark-guided Technique in Spinal Anesthesia in Orthopedic Obese Patients
|
N/A | |
Completed |
NCT06375863 -
QT Changes in Geriatric Patients: a Comparison of Spinal and General Anesthesia
|
N/A | |
Completed |
NCT02737813 -
Cardiac Output Changes During Hyperbaric and Isobaric Bupivacaine in Patients Undergoing Cesarean Section
|
Phase 4 |