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Clinical Trial Summary

This is a phase I clinical study to evaluate the safety and efficacy of CAR-T infusion preparation in the treatment of CD19-positive relapsed/refractory non-Hodgkin lymphoma.


Clinical Trial Description

This is a single-center, single-arm, open-label study. After meeting the eligibility criteria and enrolling on the trial, patients will undergo leukapheresis for collection of autologous lymphocytes. Once cells have been manufactured, patients will then proceed to lymphodepleting chemotherapy with cyclophosphamide and fludarabine for 1-2 consecutive days followed by the infusion of CAR T-cells at a target dose of 3-10x105 cells/kg. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05420493
Study type Interventional
Source Chongqing Precision Biotech Co., Ltd
Contact Jingwang Bi, M.D
Phone 13066029387
Email jingwangbi@live.cn
Status Recruiting
Phase Phase 1
Start date September 6, 2021
Completion date September 30, 2025

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