Regional Anesthesia Morbidity Clinical Trial
Official title:
Four-quadrant Transversus Abdominis Plane Block Versus Intrathecal Morphine in Gynecological Cancer Surgeries: a Single-center Retrospective Study.
| NCT number | NCT06382376 |
| Other study ID # | 2024-60 |
| Secondary ID | |
| Status | Completed |
| Phase | |
| First received | |
| Last updated | |
| Start date | June 1, 2023 |
| Est. completion date | March 1, 2024 |
| Verified date | April 2024 |
| Source | Bakirkoy Dr. Sadi Konuk Research and Training Hospital |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Observational [Patient Registry] |
The aim of this study is to compare the effectiveness of intrathecal morphine and four-quadrant transversus abdominis plane block applied for postoperative analgesia in gynecological cancer surgeries. The key question(s) it aims to answer are: [Is intrathecal morphine more effective in postoperative analgesia?] Patients who underwent gynecological cancer surgery were examined retrospectively. The investigators evaluated the effect of intrathecal morphine and four-quadrant transversus abdominis plane block applied for postoperative analgesia on pain scores and postoperative opioid use.
| Status | Completed |
| Enrollment | 71 |
| Est. completion date | March 1, 2024 |
| Est. primary completion date | December 1, 2023 |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | Female |
| Age group | 18 Years to 80 Years |
| Eligibility | Inclusion Criteria: - 18 years - Patients who have undergone gynecological cancer surgery Exclusion Criteria: - <18 years - Those with missing data |
| Country | Name | City | State |
|---|---|---|---|
| Turkey | Basaksehir Çam and Sakura City Hospital | Istanbul | Basaksehir |
| Lead Sponsor | Collaborator |
|---|---|
| Bakirkoy Dr. Sadi Konuk Research and Training Hospital |
Turkey,
Black KA, Nelson G, Goucher N, Foley J, Pin S, Chong M, Ghosh S, Bisch SP. Effect of transversus abdominis plane block on postoperative outcomes in gynecologic oncology patients managed on an Enhanced Recovery After Surgery pathway. Gynecol Oncol. 2023 No — View Citation
Meylan N, Elia N, Lysakowski C, Tramer MR. Benefit and risk of intrathecal morphine without local anaesthetic in patients undergoing major surgery: meta-analysis of randomized trials. Br J Anaesth. 2009 Feb;102(2):156-67. doi: 10.1093/bja/aen368. — View Citation
Niraj G, Kelkar A, Hart E, Kaushik V, Fleet D, Jameson J. Four quadrant transversus abdominis plane block and continuous transversus abdominis plane analgesia: a 3-year prospective audit in 124 patients. J Clin Anesth. 2015 Nov;27(7):579-84. doi: 10.1016/ — View Citation
Pirie K, Traer E, Finniss D, Myles PS, Riedel B. Current approaches to acute postoperative pain management after major abdominal surgery: a narrative review and future directions. Br J Anaesth. 2022 Sep;129(3):378-393. doi: 10.1016/j.bja.2022.05.029. Epub — View Citation
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | postoperative numerical rating scale | Our primary aim was to evaluate numerical rating scale at 24 hours postoperatively. numerical rating scale(NRS) was used to assess postoperative pain. NRS values were recorded For example, 0-10 where 0 is no pain and 10 is the worst pain imaginable. | 24 hours postoperatively | |
| Secondary | postoperative opioid use | Our secondary aim was to evaluate opioid demand and consumption amounts in the postoperative 24 hours. | 24 hours postoperatively |
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