Study to Evaluate the Safety & Efficacy of Sorafenib, in Subject With

Clinical Trial Summary

This study is a single arm, pilot study of Sorafenib in patient with BRAF mutation Refractory solid tumor and specific sensitivity to Sorafenib by Avatar scan that has progressed following standard therapy or that has not responded to standard therapy or for which there is no standard therapy.

To investigate the efficacy and safety of Sorafenib in patient with Refractory solid tumor.

See also
Status	Clinical Trial	Phase
Completed	`NCT00404508` - A Phase II Study of Epigenetic Therapy to Overcome Chemotherapy Resistance in Refractory Solid Tumors	Phase 2
Completed	`NCT02450136` - Single-arm Study to Evaluate the Safety and Efficacy of Pazopanib, in Subjects With FGFR2 Amplification, FGFR2 Mutation Refractory Solid Tumors	N/A
Completed	`NCT02596503` - A Study of Eribulin in Combination With Oral Irinotecan for Adolescent and Young Adult Patients With Relapsed or Refractory Solid Tumors	Phase 1
Completed	`NCT00759928` - PK Trial of Sorafenib & Erlotinib in Patients With Refractory Solid Tumors	Phase 1
Recruiting	`NCT06150365` - Single Arm Clinical Study on the Safety and Efficacy of Personalized KSX01-TCRT in Patients With Advanced Solid Tumors	Early Phase 1
Completed	`NCT01247168` - An Open-Label, Dose-Escalation Study of AZD2461	Phase 1
Completed	`NCT00665990` - Phase I Study of Bevacizumab and Sorafenib Combined With Low Dose Cyclophosphamide in Patients With Refractory Solid Tumors and Leukemia	Phase 1
Completed	`NCT02691793` - Study to Evaluate the Safety and Efficacy of Sunitinib, in Subject With Refractory Solid Tumors	Phase 4
Completed	`NCT02450149` - Single-arm Study to Evaluate the Safety and Efficacy of Sorafenib, in Subjects With BRAF Mutation Refractory Solid Tumors	N/A
Completed	`NCT02691767` - Study to Evaluate the Safety and Efficacy of Pazopanib, in Subject With Refractory Solid Tumors	N/A
Terminated	`NCT00664586` - A Phase 1 Continuous Intravenous Infusion Study of Terameprocol (EM-1421) in Subjects With Refractory Solid Tumors	Phase 1
Recruiting	`NCT05811975` - KSX01-TCRT Injection Project in Solid Tumors	Early Phase 1
Completed	`NCT03810742` - Nanoliposomal Irinotecan (Nal-IRI, ONIVYDE®) in Combination With TAS-102 (LONSURF®) in Refractory Solid Tumors	Phase 1
Terminated	`NCT03096340` - Safety and Pharmacokinetic Study of IT-141 in Monotherapy in Patients With Advanced Cancer	Phase 1
Completed	`NCT02450123` - Single-arm Study to Evaluate the Safety and Efficacy of Sunitinib, in Subjects With RET Fusion Positive or FGFR2 Amplification, Refractory Solid Tumors	N/A
Completed	`NCT02383368` - A Dose Escalation and Expansion Study of ASP4132 to Subjects With Advanced Refractory Tumors and Lymphoma	Phase 1
Completed	`NCT00394446` - Phase 1, Multiple Dose Study of MPC-6827 in Subjects With Refractory Solid Tumors	Phase 1
Completed	`NCT03052205` - A Study of Intratumoral IMO-2125 in Patients With Refractory Solid Tumors	Phase 1
Completed	`NCT02482441` - A Phase 1a/b Dose Escalation Study of the Safety, Pharmacokinetics, and Pharmacodynamics of OMP-131R10	Phase 1
Recruiting	`NCT03739827` - Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors

NCT number	NCT02691780
Study type	Interventional
Source	Samsung Medical Center
Contact
Status	Withdrawn
Phase	N/A
Start date	December 23, 2016
Completion date	November 19, 2019

Study to Evaluate the Safety and Efficacy of Sorafenib, in Subject With Refractory Solid Tumors

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms