CPC in Adult Refractory Glaucoma

Refractory Glaucoma Clinical Trial

Official title:

Evaluation of Diode Laser Cyclophotocoagulation in Adult Refractory Glaucoma

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04921098
• Other study ID #: Soh-Med-21-05-01
• Status: Recruiting
• Phase: N/A
• Start date: July 1, 2021
• Est. completion date: April 2022

Study information

• Verified date: January 2022
• Source: Sohag University
• Contact: Mina A Besada, Resident
• Phone: 01280899267
• Email: mena011205[@]med.sohag.edu.eg
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to assess the relative effectiveness and safety of diode laser cyclophotocoagulation procedure to reduce IOP and relieve pain in adult patients with refractory glaucoma.

Description:

A hospital -based, prospective interventional non comparative case series study.This study will be conducted on patients with refractory glaucoma whose ages are 18 years and older.They will be subjected to Transscleral Diode Laser Cyclophotocoagulation.

Postoperative evaluation will be scheduled for the first day postoperative, then 1 week later and then at 1st, 3rd, month postoperative.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 25
• Est. completion date: April 2022
• Est. primary completion date: April 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Inclusion Criteria:

1. Patients with refractory glaucoma aging 18 years and older.

2. Both sexes are included.

3. Patients Capable of giving informed consent.

4. Pseudophkic glaucoma.

5. Aphakic glaucoma.

6. Silicon oil induced glaucoma.

7. Neovascular glaucoma.

8. Inflammatory glaucoma.

Exclusion Criteria:

1. Patients <18 years of age.

2. Patients controlled on regular antiglaucomatous therapy.

3. Patients who cannot do regular follow up visits.

4. Diffuse scleral staphyloma at the site of CPC.

Related Conditions & MeSH terms

• Glaucoma
• Refractory Glaucoma

Intervention

Procedure:
• Diode Laser Cyclophotocoagulation
A handpiece (G probe) is used to deliver the diode laser energy with a wavelength of 810 nm.

Locations

Country	Name	City	State
Egypt	Sohag University	Sohag

Sponsors (1)

Lead Sponsor	Collaborator
Sohag University

Country where clinical trial is conducted

Egypt, 

References & Publications (3)

Ansari E, Gandhewar J. Long-term efficacy and visual acuity following transscleral diode laser photocoagulation in cases of refractory and non-refractory glaucoma. Eye (Lond). 2007 Jul;21(7):936-40. Epub 2006 Apr 21. — View Citation

Lai JS, Tham CC, Chan JC, Lam DS. Diode laser transscleral cyclophotocoagulation in the treatment of chronic angle-closure glaucoma: a preliminary study. J Glaucoma. 2003 Aug;12(4):360-4. — View Citation

Nassiri N, Kamali G, Rahnavardi M, Mohammadi B, Nassiri S, Rahmani L, Nassiri N. Ahmed glaucoma valve and single-plate Molteno implants in treatment of refractory glaucoma: a comparative study. Am J Ophthalmol. 2010 Jun;149(6):893-902. doi: 10.1016/j.ajo.2010.01.025. Epub 2010 May 8. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	change in intraocular pressure	IOP measuring using Goldmann applanation tonometer.	First day postoperative and 1 week