Jinghua Weikang Capsule in the Treatment of Reflux Esophagitis

Status Not yet recruiting

Clinical Trial Summary

Reflux esophagitis is a common clinical disease ; pPI or potassium competitive acid blocker ( P-CAB ) is the first choice for the treatment of reflux esophagitis. However, patients with recurrent symptoms and severe esophagitis ( Los Angeles grade C and D ) after long-term use of PPI or P-CAB usually need long-term maintenance treatment. Attention should be paid to the possible adverse reactions of long-term acid suppression therapy and the interaction between drugs. The main efficacy of Jinghua Weikang capsules is regulating qi and dispersing cold, clearing heat and removing blood stasis. Applicable to cold and heat syndrome, qi stagnation and blood stasis caused by epigastric distension, pain, belching, acid reflux, noisy, bitter taste ; duodenal ulcer see the above syndrome. In the early stage, a series of studies were carried out on Jinghua Weikang Capsule, which confirmed that Jinghua Weikang Capsule showed the effect of acid inhibition and symptom relief in the treatment of reflux esophagitis, and had a synergistic effect when combined with western medicine. However, Jinghua Weikang Capsule still lacks sufficient evidence to support the reduction of the recurrence rate of reflux esophagitis. Therefore, we carried out this experiment to explore the clinical efficacy of Jinghua Weikang Capsule in the maintenance treatment of reflux esophagitis, so as to reduce the recurrence rate of reflux esophagitis and relieve symptoms.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06056973
Study type	Interventional
Source	The First Affiliated Hospital of Dalian Medical University
Contact
Status	Not yet recruiting
Phase	Phase 4
Start date	October 1, 2023
Completion date	October 1, 2025

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT06170060` - Treatment of Reflux With Sleeve Gastrectomy	N/A
Not yet recruiting	`NCT06062225` - Protocol for Comparing the Efficacy of Three Reconstruction Methods of the Digestive Tract After Proximal Gastrectomy	N/A
Completed	`NCT01964131` - BE Study Between a Capsule and a Sachet Formulation of D961H by Pharmacodynamics in Japanese Healthy Male Subjects	Phase 1
Completed	`NCT01008696` - An Efficacy Study to Compare the Treatment Effects of Rabeprazole and Lansoprazole Depending on the Genotyping of CYP2C19 in Treating Reflux Esophagitis	Phase 4
Recruiting	`NCT05899491` - Role of ARMA in Selective Subset of Refractory GERD Patients.	N/A
Recruiting	`NCT01311908` - Incidence of Reflux Esophagitis After Pancreaticoduodenectomy	N/A
Completed	`NCT03214081` - Special Drug Use Surveillance of Vonoprazan for "Maintenance Therapy of Reflux Esophagitis: Long-term Use"
Not yet recruiting	`NCT01560598` - Adipokines and the Risk of Reflux Esophagitis	N/A
Completed	`NCT00859287` - Omepral® Tablets Special Clinical Experience Investigation in Patients With Erosive Esophagitis	N/A
Completed	`NCT00206180` - NEXIUM® in the Treatment of Moderate and Severe Erosive Esophagitis	Phase 4
Recruiting	`NCT04657848` - Preliminary Efficacy Analysis of Cheng's Giraffe Reconstruction After Proximal Gastrectomy	N/A
Completed	`NCT02477475` - Nexium Capsules S-CEI for Justification of Esomeprazole in Acid Related Disease for Reflux Symptom Healing Based on Patient Clinical Outcomes	N/A
Completed	`NCT03553563` - A Study of Esomeplazole (D961H) in Japanese Paediatric Patients With Reflux Esophagitis, Gastric Ulcer or Duodenal Ulcer	Phase 3
Completed	`NCT01381991` - The Efficacy of i-Scan for Detecting Reflux Esophagitis	N/A
Completed	`NCT04673643` - Transcutaneous Auricular Vagus Nerve Stimulation Treatment on Reflux Esophagitis	N/A
Recruiting	`NCT04531475` - Study to Evaluate the Safety and Efficacy of X842 in Patients With Reflux Esophagitis	Phase 2
Completed	`NCT00634114` - Reflux Esophagitis Phase III Study (Maintenance Treatment)	Phase 3
Completed	`NCT00586963` - Proton Pump Inhibitor (PPI) Therapy for Newly Diagnosed Esophagitis	N/A
Completed	`NCT03388047` - Feasibility of Multi-Spectral Endoscopic Imaging for Detection of Early Neoplasia in Barrett's Oesophagus	N/A
Recruiting	`NCT00155805` - Immunologic Factors in Reflux Esophagitis and Barrett’s Esophagus	N/A