Recurrent Small Lymphocytic Lymphoma Clinical Trial
Official title:
Phase II Study of 506U78 (NSC #686673) for Patients With Relapsed or Refractory Indolent B-Cell or Peripheral T-Cell Lymphoma
Phase II trial to study the effectiveness of 506U78 in treating patients who have recurrent or refractory non-Hodgkin's lymphoma or T-cell lymphoma. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die
OBJECTIVES:
I. Determine the response rate, failure-free survival, and progression-free survival of
patients with recurrent or refractory indolent B-cell non-Hodgkin's lymphoma or peripheral
T-cell lymphoma when treated with 506U78.
II. Assess the pharmacokinetics and toxicity of this treatment in these patients.
OUTLINE:
Patients receive 506U78 IV over 2 hours on days 1, 3, and 5. Treatment repeats every 28 days
for up to 6 courses in the absence of disease progression or unacceptable toxicity.
Patients are followed every 3 months.
;
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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