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Clinical Trial Summary

Increased glucose metabolism is characteristic for solid tumors. Thereby, glucose is important for the generation of ATP, supply of anabolic substrates and defense against reactive oxygen species in tumor cells. In preclinical models, restricting glucose availability using a ketogenic diet, calorie-restriction or transient fasting inhibits tumor growth. Therefore, the purpose of the study is to evaluate whether a calorie-restricted, ketogenic diet and transient fasting can enhance the efficacy of reirradiation in patients with recurrent glioblastoma.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT01754350
Study type Interventional
Source Johann Wolfgang Goethe University Hospital
Contact
Status Completed
Phase N/A
Start date May 2013
Completion date March 2019

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