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PREventing Second Cancers With DOSTARlimab — PREDOSTAR  

Recurrent Cancer Clinical Trial

Official title:
A Multicenter, Open-label, Randomized Phase II Study Aiming to Assess the Clinical Impact of Dostarlimab on Occurrence of Second Primary Cancer in Patients With Cured Primary Cancer

Clinical Trial Summary

PredoSTAR is a multicenter, randomized, open-label phase II study proposed to patients at high risk of SPC and in whom the treatment of the FPC does not include immunotherapy. Dostarlimab treatment will be started within 6 months after the completion of treatment for localized FPC (i.e. after the end of last CT, RT cure or surgery with a wash-out period of 4 weeks before to start Dostarlimab). Eligible patients will be randomized (1:1) to receive: - Arm Dostarlimab : 4 intravenous (IV) injections of dostarlimab, Q3W or - Arm No treatment

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05855811
Study type Interventional
Source Centre Leon Berard
Contact Jean-Yves BLAY, MD, PhD
Phone 4 78 78 51 26
Email jean-yves.blay@lyon.unicancer.fr
Status Recruiting
Phase Phase 2
Start date July 26, 2023
Completion date March 26, 2029
View Details
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