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Clinical Trial Summary

This prospective, single-arm study is conducted to investigate the safety and efficacy of Sintilimab combined with hypofractionated radiotherapy in patients with microsatellite instability-high (MSI-H)/ DNA mismatch repair-deficient (dMMR) non-metastatic rectal cancer.


Clinical Trial Description

The patients meet the inclusion criteria. After signing the informed consent, they are given radiotherapy 5Gyx5 and sintilimab 200mg ivgtt D1, D15, D29. Radical surgery is performed 6-8 weeks after radiotherapy. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04636008
Study type Interventional
Source West China Hospital
Contact Xiaofen Li, M.D.
Phone +86-28-85422589
Email lxf0827@163.com
Status Recruiting
Phase Phase 1/Phase 2
Start date August 14, 2020
Completion date November 2022

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