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Intact Cord Resuscitation in CDH — CHIC  

Rare Diseases Clinical Trial

Official title:
Efficacy of Intact Cord Resuscitation Compared to Immediate Cord Clamping on Cardiorespiratory Adaptation at Birth in Infants With Isolated Congenital Diaphragmatic Hernia (CDH)

Clinical Trial Summary

Isolated CDH is a rare disease (1/3500) and displays a wide range of severity and outcome. Despite attempts to standardize the management of this disease at birth and during the first months of life, the mortality varies from 20 to 50% according to different hospitals in France and abroad. Several studies already showed the benefice of late cord clamping at birth on biological and physiological adaptation of newborns to life. Previous works also suggest a possible benefit of this procedure for babies with CDH. This multicenter randomized clinical study aims to investigate the efficacy of intact cord resuscitation compared to immediate cord clamping on cardiorespiratory adaptation at birth in full term newborn infants with isolated CDH.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04429750
Study type Interventional
Source University Hospital, Lille
Contact Laurent Storme, MD,PhD
Phone 03 20 44 61 99
Email laurent.storme@chru-lille.fr
Status Recruiting
Phase N/A
Start date October 8, 2020
Completion date October 2025
View Details
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