Lung Dispersing, Turbid Descending and Gut Clearing Decoction for Bronchiectasis — LUNG-CLEAR  

Quality of Life Clinical Trial

Official title: Efficacy and Safety of Lung Dispersing, Turbid Descending and Gut Clearing Decoction on Clinically Stable Bronchiectasis (LUNG-CLEAR): A Multicenter, Randomized, Cross-over Trial

Status Not yet recruiting

Clinical Trial Summary

Bronchiectasis is a chronic airway disease which confers significant healthcare burden, with limited therapeutic approaches. From the perspective of traditional Chinese medicine, congenital insufficiency of the lung, spleen and kidney, when coupled with external injury or mood impairment, may collectively contribute to bronchiectasis pathogenesis due to heat trapping in the phlems, congestion of wind evils and stagnation of blood. Here, the investigators will explore the Lung Dispersing, Turbid Descending and Gut Clearing Decoction (LTGD) which targets at expelling the wind evil in patients with bronchiectasis. The investigators sought to conduct a multicenter, randomized cross-over trial which investigates the efficacy and safety of LTGD on clinically stable bronchiectasis.

Clinical Trial Description

Bronchiectasis is a chronic airway disease which confers significant healthcare burden, with limited therapeutic approaches. From the perspective of traditional Chinese medicine, congenital insufficiency of the lung, spleen and kidney, when coupled with external injury or mood impairment, may collectively contribute to bronchiectasis pathogenesis due to heat trapping in the phlems, congestion of wind evils and stagnation of blood. Symptomatic treatment may be effective and safe for ameliorating respiratory symptoms and hindering disease progression of bronchiectasis. Here, the investigators have explored the Lung Dispersing, Turbid Descending and Gut Clearing Decoction (LTGD) which targets at expelling the wind evil in patients with bronchiectasis. The investigators sought to conduct a multicenter, randomized cross-over trial which investigates the efficacy and safety of LTGD on clinically stable bronchiectasis. ;

Related Conditions & MeSH terms

• Bronchiectasis
• Bronchiectasis Adult
• Exacerbation
• Quality of Life
• Traditional Chinese Medicine

• NCT number: NCT03177889
• Study type: Interventional
• Source: Guangzhou Institute of Respiratory Disease
• Contact: Wei-jie Guan, Ph.D.
• Phone: +86-13826042052
• Email: battery203@163.com
• Status: Not yet recruiting
• Phase: N/A
• Start date: December 31, 2021
• Completion date: December 31, 2023