Anterior vs. Posterior Quadratus Lumborum Block in Nephrectomy Patients

Status Not yet recruiting

Clinical Trial Summary

- Primary outcome: to compare the efficacy of Anterior subcostal versus Posterior approach in ultrasound guided Quadratus Lumborum Block.

- Secondary outcome: to evaluate the efficacy of Quadratus Lumborum Block in the control of postoperative pain in patients undergoing Nephrectomy surgery, hemodynamics, any complications and patients' satisfaction..

Clinical Trial Description

A variant of the ultrasound-guided transversus abdominis plane (TAP) block was first described in an abstract, in which local anesthetic injection occurs at the point where the internal oblique and transversus abdominis muscles taper off and adjoin the lateral border of quadratus lumborum (QL) muscle.

Currently, the QL block is performed as one of the perioperative pain management procedures for all generations (pediatrics, pregnant, and adult) undergoing abdominal surgery.

However, there is large disagreement regarding the best approach for administering the block because of unclear mechanisms responsible for the effects and complicated nomenclature system. Nephrectomy for patients with renal cell carcinoma (RCC) was first described in 1969. Surgical treatment varies with the pathology. Simple nephrectomy is the preferred option for those with non-neoplastic disease (e.g. trauma, non-functioning kidney with chronic infection) with radical nephrectomy being preferred in those with neoplastic disease. Radical nephrectomy implies resection of the whole of Gerota's fascia, including the perinephric fat, lymphatics, and the ipsilateral adrenal gland. Here the investigators are going to compare the Anterior (subcostal) approach to the Posterior approach to determine their level of spread and their value in controlling postoperative pain in patients scheduled for Nephrectomy surgery. ;

Study Design

Related Conditions & MeSH terms

Quadratus Lumborum Block

Clinical Trial Details

NCT number	NCT03973398
Study type	Interventional
Source	Assiut University
Contact	Sherif Bekhet
Phone	00201155538773
Email	bekhetsherif89@gmail.com
Status	Not yet recruiting
Phase	Early Phase 1
Start date	July 1, 2020
Completion date	September 1, 2021

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05465967` - Transmuscular Quadratus Lumborum Block on Post-Operative Analgesia After Total Hip Arthroplasty	N/A
Completed	`NCT03199170` - Effect of Bilateral Quadratus Lumborum Block for Pain Relief in Patients With Cesarean Section	N/A
Completed	`NCT03695588` - Quadratus Lumborum Block (QLB) for Pain Relief After Caesarean Section	N/A
Not yet recruiting	`NCT05089994` - Comparison of Two Approaches of Quadratus Lumborum Block for Post-operative Analgesia in Radical Cystectomy	N/A
Recruiting	`NCT05158270` - Erector Spinae Plane Block As Alternative Analgesic Modality in Laparoscopic Cholecystectomy	N/A
Recruiting	`NCT03540537` - A Trial Comparing Quadratus Lumborum Block (QLB) and Paravertebral Block (PVTB) for Postoperative Analgesia in Hepatectomy	N/A
Recruiting	`NCT03328481` - Quadratus Lumborum Block Using Loss-of-resistance Versus Ultrasound-guided Technique	N/A
Not yet recruiting	`NCT04845711` - Ultrasound Guided Erector Spinae Plane Block Versus Quadratus Lumborum Block in Laparoscopic Cholecystectomy	N/A
Enrolling by invitation	`NCT04822870` - Comparison of Ultrasound-guided Quadratus Lumborum Block and Iliohypogastric/Ilioinguinal Nerve Block for Postoperative Pain Management in Patients Undergoing Cesarean Section	N/A
Completed	`NCT05950568` - Quadratus Lumborum Block Type III Versus Type II Versus Transversus Abdominis Plane Block in Cesarean Section	N/A
Recruiting	`NCT04670224` - Efficiency of the Quadratus Lumborum Block for Post-operative Analgesia in Abdominoplasty Surgery	N/A
Recruiting	`NCT04830280` - Effect Posterior QLB on Atelectasis	N/A
Not yet recruiting	`NCT05416866` - Transversus Abdominis Plane Block Plus Quadratus Lumborum Block or Retrolaminar Block of Multiple Injections for Postoperative Analgesia Following Laparoscopic Colorectal Surgery	Phase 4
Completed	`NCT04963816` - Pediatric Postoperative Analgesia With Quadratus Lumborum Block(QLB) And Dexamethasone As An Adjuvant To Bupivacaine.	N/A
Recruiting	`NCT04402411` - Quadratus Lumborum Block vs Transversus Abdominis Plane Block in Bladder Cancer Surgeries	N/A
Completed	`NCT05713643` - ESPB vs PVB vs QLB After Pelvi-ureteric Surgeries	N/A
Completed	`NCT03496610` - Surgeon Infiltration QL Block Comparison	Phase 4
Completed	`NCT03437187` - The Beneficial Effect of Quadratus Lumborum Block After Laparoscopic Cholecystectomy	N/A
Recruiting	`NCT06155968` - Evaluating The Quality of Recovery After Elective Cesarean Section	N/A
Not yet recruiting	`NCT05442905` - Quadratus Lumborum Versus Transversus Abdominis Plane Block Versus Caudal Block for Postoperative Analgesia After Pediatric Inguinal Hernia : Double-Blinded Randomized Trial	N/A