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Acute Exposure to High Altitude on Blood and Tissue Oxygenation (ABGA, NIRS)

Pulmonary Hypertension Clinical Trial

Official title:
Acute Exposure to Hypoxia in Precapillary Pulmonary Hypertension: Physiological and Clinical Effects at Rest and During Exercise

Clinical Trial Summary

Randomized crossover Trial in patients with Pulmonary Hypertension (PAH, CTEPH) to assess the acute response to High Altitude (2500m above sea level) on blood and tissue oxygenation (ABGA, NIRS).

Clinical Trial Description

Low altitude baseline measurements will be performed in Zurich (460m asl) including Echocardiography, Right heart catheterization, 6MWT, pulmonary function test, clinical assessment and blood gas Analysis.

Randomly assigned to the order of testing, the participants will be tested in Low Altitude (Zurich, 470m) and at High Altitude (2500m).

At rest and under exercise data from ABGA and NIRS will be compared at low altitude and High Altitude. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03600415
Study type Interventional
Source University of Zurich
Contact
Status Completed
Phase N/A
Start date July 1, 2018
Completion date January 1, 2019
View Details
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