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Acute Excposure of High Altitude on ECG and Non-invasive Blood Pressure.

Pulmonary Hypertension Clinical Trial

Official title:
Acute Exposure to Hypoxia in Precapillary Pulmonary Hypertension: Physiological and Clinical Effects at Rest and During Exercise

Clinical Trial Summary

Randomized crossover trial in patients with Pulmonary Hypertension (PAH, CTEPH) to assess the acute response of High Altitude (Säntis, 2500m above sea level) on ECG repolarizations and non-invasive blood pressure measurements by Finapres® NOVA Technology.

Clinical Trial Description

Low altitude baseline measurements will be performed in Zurich (460m asl) including Echocardiography, Right heart catheterization, 6MWT, pulmonary function test, clinical assessment and blood gas Analysis.

Randomly assigned to the order of testing, the participants will be tested in Low Altitude (Zurich, 470m) and at High Altitude (2500m).

During the exposure High Alitude (2500m above sea level) and low alitude (Zurich) up to 5 hours, the participants' ECG and non-invasively assessed blood pressure by Finapres at rest and under exercise will be collected. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03593083
Study type Interventional
Source University of Zurich
Contact
Status Completed
Phase N/A
Start date July 1, 2018
Completion date January 1, 2019
View Details
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