Inspiratory Muscle Training in Pulmonary Hypertension

Pulmonary Hypertension Clinical Trial

Official title:

The Effects of Inspiratory Muscle Training on Exercise Capacity, Physical Activity and Quality of Life in Pulmonary Hypertension

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03385733
• Other study ID #: GAslan
• Secondary ID: BuketA
• Status: Completed
• Phase: N/A
• First received: December 21, 2017
• Last updated: February 28, 2018
• Start date: October 10, 2017
• Est. completion date: February 15, 2018

Study information

• Verified date: February 2018
• Source: Istanbul University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of this study is to investigate the effective of inspiratory muscle training on respiratory function, exercise capacity, physical activity and quality of life.

Description:

Pulmonary hypertension (PH) is a condition which is seen with hemodynamic differences, pulmonary vascular resistance and right heart failure. Patients with pulmonary hypertension have, dyspnea, physical inactivity, reduced condition and respiratory muscle dysfunction. Aerobic exercise programs in patients with pulmonary hypertension are reported to result in improved exercise capacity and endurance of the patients, improvement in WHO functional class and quality of life, increased peak workload and increased peripheral muscle function. In recent years, few studies have investigated the efficacy of inspiratory muscle training in patients with PH.The aim of this study is to investigate the effective of inspiratory muscle training on respiratory function, exercise capacity, physical activity and quality of life.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 30
• Est. completion date: February 15, 2018
• Est. primary completion date: February 15, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• Diagnosis of Pulmonary Hypertension,

• NYHA functional class I-IV

• MIP pressure <80 cm h2O

Exclusion Criteria:

• COPD

• Conditions which can limit the assessments

• Insufficient cooperation

Related Conditions & MeSH terms

• Hypertension
• Hypertension, Pulmonary
• Pulmonary Hypertension
• Respiratory Aspiration

Intervention

Other:
• inspiratory muscle training
The treatment group received IMT. Patients were trained using an inspiratory threshold-loading device

Locations

Country	Name	City	State
Turkey	Istanbul University	Istanbul

Sponsors (2)

Lead Sponsor	Collaborator
Istanbul University	Biruni University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	mouth pressures	MIP and MEP	10 minutes
Secondary	International Physical Activity Questionnaire-Short Form	Physical activity	10 minutes
Secondary	Minnesota Living with Heart Failure Questionnaire	quality of life	15 minutes
Secondary	Activity monitoring (Sense wear® Armband)	Metabolic holter	3 days
Secondary	6 minute walking test	functional capacity	15 minutes