Registration Study for Rare Type of Pulmonary Hypertension

Pulmonary Hypertension Clinical Trial

Official title: Registration Study for Rare Type of Pulmonary Hypertension

Status Recruiting

Clinical Trial Summary

The knowledge on the rare type of pulmonary hypertension which can not be explained by left heart disease, respiratory disease or congenital heart disease is very limited. Investigators aim to setup a national registration study for the rare type of pulmonary hypertension, to understand the natural history, survival, progression, genetic and environmental contributions to disease.

Clinical Trial Description

The main research contents of this registration study includes:

1. Build a baseline database of the rare type of pulmonary hypertension. Collect general information, on-set symptoms and time, laboratory examination, imaging results, right heart catheterization and treatment information.

2. Follow up recruited patients at regular intervals（6m~1y). Collect information on change in patients condition, laboratory test and treatment.

3. Conduct genetic testing for gene mutation related or hereditary pulmonary hypertension. Link the clinical database to genetic database.

4. Establish bio-bank for serum/plasma, urine, stool, tissues or cells.

5. Establish prognostic study based on the clinical follow-up and genetic database.

6. Draw diagnostic and treatment algorithm for the rare type of pulmonary hypertension.

Controls subjects: blood sample and medical data collected once. ;

Related Conditions & MeSH terms

• Hypertension
• Hypertension, Pulmonary
• Pulmonary Hypertension

• NCT number: NCT03169010
• Study type: Observational [Patient Registry]
• Source: China National Center for Cardiovascular Diseases
• Contact: Xi-Qi XU, MD. PhD.
• Phone: +861088322267
• Email: xuxiqi0928@163.com
• Status: Recruiting
• Start date: May 6, 2017
• Completion date: December 31, 2040