Pulmonary Hypertension Clinical Trial
Official title:
Smoking: a Risk Factor for Pulmonary Arterial Hypertension? A D-A-CH Pulmonary Hypertension Study (Germany- Austria - Switzerland)
Environmental factors may play a role in the genesis of pulmonary hypertension, especially
in endothelial dysfunction. One widespread environmental factor associated with systemic
endothelial dysfunction is cigarette smoke. It may well be that cigarette smoking is not
only a risk factor for systemic but also for pulmonary vascular diseases and herewith may
interact with other risk factors such as a genetic background and associated conditions. The
existing studies which deal with this subject are only small single center case control
studies providing less data. Therefore a large European multicenter study is necessary.
The investigators hypothesis are:
- a history of tobacco smoke exposure is highly prevalent in patients with PAH compared
to the unaffected general population.
- a history of tobacco smoke exposure is more prevalent in patients with PAH compared to
CTEPH.
n/a
Observational Model: Case Control, Time Perspective: Prospective
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