Effects of Different Oxygen Concentrations on Lung Ultrasound Score During

Status Completed

Clinical Trial Summary

The goal of this study is to observe the effects of different oxygen concentrations during preoxygenation in spontaneous breathing patients with modified lung ultrasound scores before induction of general anesthesia. Preoxygenation is a routine and recommended procedure for patients undergoing general anesthesia. Atelectasis is a common side effect of general anesthesia and usage of high concentration oxygen is a probable cause of it. Using lower oxygen concentrations in preoxygenation may help reducing the atelectasis and it can be assessed by lung ultrasound.

Clinical Trial Description

Preoxygenation is the process of supplying the patient a high inspired fraction of oxygen prior to an airway intervention or induction of general anesthesia. Prolonging safe apnea duration is the primary aim of preoxygenation and preoxygenation is recommended for all patients before induction of general anesthesia. Atelectasis is the most common postoperative pulmonary complication and is associated with usage of high inspired fraction of oxygen. Modified lung ultrasound scoring is an effective and noninvasive method to determine atelectasis. In this study we will observe the effects of different oxygen concentrations during preoxygenation before induction of general anesthesia in spontaneous breathing patients with modified lung ultrasound scores . Patients undergoing general anesthesia for elective surgery meeting the criteria will be acknowledged about the study. After written consents are taken patients will be randomised into two groups by coin method. One group will receive %80 oxygen for 3 minutes and other group will receive %100 oxygen for 3 minutes during preoxygenation. Each participants demographic data will be collected. 12 quadrants of thorax divided by midsternal line, anterior axillary and posterior axillary lines will be examined by the usage of modified lung ultrasound score before and at the end of preoxygenation for all individuals. Randomisation, lung ultrasound scoring and preoxygenation will be done by different experienced anesthesiologists so the observers of this study would be blinded for the results. Patients will be blinded for the concentration of oxygen. Modified lung scores of each group would be compared at the end of the study. ;

Study Design

Related Conditions & MeSH terms

Pulmonary Atelectasis

Clinical Trial Details

NCT number	NCT05850988
Study type	Interventional
Source	Diskapi Teaching and Research Hospital
Contact
Status	Completed
Phase	N/A
Start date	April 15, 2023
Completion date	June 1, 2023

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02870842` - Fraction of Inspired Oxygen and Atelectasis in Children	N/A
Withdrawn	`NCT02952066` - Expressions of TRPV1 in Airway of Asthmatics	N/A
Recruiting	`NCT03311347` - Atelectasis Formation: Role of Positive Pressure Breathing, Hyperoxia, and Hypobaria	N/A
Completed	`NCT04116567` - Lung Ultrasonography After Laparoscopic Gynecologic Surgery
Completed	`NCT02584023` - Lung Ultrasound and Alveolar Recruitment in Mechanically Ventilated Infants	N/A
Recruiting	`NCT06205212` - High-flow Nasal Oxygenation During Preoxygenation and Atelectasis	N/A
Completed	`NCT04566419` - poStoperative Anesthesia Care: Facial Mask vs Hfnc and Thoracic Ultrasound for Reduction of Atelectasis Incidence	N/A
Completed	`NCT04993001` - Impact of an Open Lung Extubation Strategy on Postoperative Pulmonary Complications	N/A
Completed	`NCT03630484` - Ventilator Hyperinflation and Manual Rib Cage Compression	N/A
Completed	`NCT02262182` - Interest of Positive Expiratory Pressure (PEP) Delivery by EzPAP® After Cardiac Surgery in the Management of Postoperative Atelectasis	N/A
Completed	`NCT01476254` - Respiratory Complications After Laparoscopic Surgery	N/A
Not yet recruiting	`NCT04566172` - Preoperative Optimization to Improve Functional Status	N/A
Completed	`NCT03763461` - HFNC During Awake Craniotomy - Impact on Patient Comfort	N/A
Enrolling by invitation	`NCT05434624` - QT Distance and P Dispersion in ECG in Patients Having Bronchoscopy in the ICU	N/A
Withdrawn	`NCT02070445` - Ventilation During Cardiopulmonary Bypass (CPB) for Cardiac Surgery
Recruiting	`NCT02431455` - The Effect of Postoperative Incentive Spirometry on Pulmonary Function and Pulmonary Complications in Bariatric Surgery	N/A
Completed	`NCT03686631` - The Digital Incentive Spirometer (DIS): Improving Adherence to Incentive Spirometry	N/A
Active, not recruiting	`NCT03009331` - Descriptive and Comparative Study of Respiratory Function in the Postoperative Cardiac Surgery Patient	N/A
Recruiting	`NCT01289691` - Atelectasis After Pulmonary Lobectomy: The Effect Of Air During One-Lung Ventilation (OLV) On Postoperative Atelectasis	N/A
Active, not recruiting	`NCT05077111` - A Comparative Study Between Regional Anesthesia in Thoracoscopes and the Conventional General Anesthesia	Phase 4

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Effects of Different Oxygen Concentrations on Lung Ultrasound Score During Spontaneous Ventilation

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms