PTSD Clinical Trial - Ketamine-enhanced Prolonged Exposure Therapy in PTSD

Status Recruiting

Clinical Trial Summary

The purpose of this study is to test the safety and efficacy of repeated doses of ketamine as compared to placebo to reduce symptoms of Posttraumatic Stress Disorder (PTSD) among Veteran receiving Prolonged Exposure Therapy.

Clinical Trial Description

In this single site clinical trial, intended to evaluate the safety and efficacy of repeated doses of ketamine in conjunction with prolonged exposure (PE) therapy for PTSD. Veterans who meet criteria for PTSD and the additional inclusion and exclusion criteria will be randomized to one of two treatment arms (placebo plus PE vs ketamine plus PE). Participants receive the study drug via intravenous infusion once per week for 3-weeks. ;

Study Design

Related Conditions & MeSH terms

PTSD

Clinical Trial Details

NCT number	NCT04560660
Study type	Interventional
Source	VA Office of Research and Development
Contact	Paulo R Shiroma, MD
Phone	(612) 725-2000
Email	Paulo.Shiroma@va.gov
Status	Recruiting
Phase	Phase 2
Start date	March 9, 2021
Completion date	October 31, 2025

View Details

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