Cognitive Processing Therapy vs. Sertraline for the Treatment of PTSD & SUD in Egyptian Patients

Psychologic Manipulation Clinical Trial

Official title:

Cognitive Processing Therapy Versus Sertraline for the Treatment of Post-traumatic Stress Disorder & Substance Use Disorder Egyptian Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03469128
• Other study ID #: 2016-2017PTBUE
• Secondary ID: IRB Protocol CL-
• Status: Completed
• Phase: Phase 1
• Start date: January 1, 2016
• Est. completion date: January 1, 2020

Study information

• Verified date: March 2021
• Source: British University In Egypt
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The present research was aimed at comparing the effects of Cognitive Processing Therapy (CPT) with the effects of Sertraline in treating patients who have dual diagnosis PTSD & SUD. The present study examines the extent to which CPT is effective in treating PTSD symptoms for patients with PTSD and SUD.

Description:

Patients with co-occurrence PTSD & SUD disorders were grouped into 3 groups: first: Cognitive Processing Therapy (CPT) in which participants completed 12 sessions of CPT. Second: were treated by Sertraline. Third: a placebo control group.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 150
• Est. completion date: January 1, 2020
• Est. primary completion date: January 1, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Patients diagnosed with SUD

Exclusion Criteria:

• Patients diagnosed with other psychotic disorders

Related Conditions & MeSH terms

• Psychologic Manipulation

Intervention

Behavioral:
• Cognitive processing therapy
Psychological treatment for patients suffering from PTSD and SUD symptoms.

Drug:
• Sertraline
Sertraline for the treatment of post-traumatic stress and SU disorders

Other:
• Placebo Control
Placebo Control

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
British University In Egypt

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Questionnaire	A psychological parameter will be measured to check the efficacy of CPT against medication for the treatment for co-current PTSD & SUD. The groups will be examined to show if any significant reductions in PTSD and SUD symptoms was obtained over time.	3 Months