Source Monitoring Déficit in Neuropsychiatric Population

Status Recruiting

Clinical Trial Summary

the investigators will measure source-monitoring ability in patients with several neuropsychiatric condition and in healthy controls appaired in age, sex and educational level. Source-monitoring will be measured thanks to internal- and reality-monitoring informatic tasks.The investigators hypothesized patients with fronto-temporal abnormalities would show more marked deficits than patients with only frontal abnormalities.

Clinical Trial Description

Source-monitoring abilities will be measured thanks to reality-monitoring testing (i.e. the ability to distinguish internal-generated events from external ones) and internal-monitoring testing (i.e. the ability to distinguish an imagined source from a performed one). A source-monitoring deficit have been demonstrated in patients with psychiatric conditions such as schizophrenia and seems linked to frontotemporal abnormalities (frontotemporal dysconnectivity and temporal hypoactivity). With a total of 150 patients, the investigators will include 30 patients per group: patients with pre-dementia stage Alzheimer, Alzheimer, Fronto-Temporal dementia, Lewy Body dementia or Parkinson and Bipolar Disorder, with the hypothesis that Bipolar Disorder patients will present less marked deficit. The investigators will recruit 150 healthy controls. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03886584
Study type	Interventional
Source	Hôpital le Vinatier
Contact	JEROME BRUNELIN, PHD
Phone	00334 37 91 55 65
Email	jerome.brunelin@ch-le-vinatier.fr
Status	Recruiting
Phase	N/A
Start date	March 8, 2019
Completion date	December 31, 2023

View Details

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