The Disease Severity In Patients With Psoriasis

Psoriasis Clinical Trial

Official title:

The Disease Severity In Patients With Psoriasis

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05943405
• Other study ID #: NAP07
• Status: Completed
• Start date: June 1, 2022
• Est. completion date: December 30, 2022

Study information

• Verified date: July 2023
• Source: Universitas Sebelas Maret
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This observational study aims to evaluate new markers to predict disease activity in psoriasis. The main question is SGOT, SGPT, GGT, hs-CRP, and apo B related to disease severity in psoriasis.

Description:

Psoriasis patients who had signed an informed consent were assessed for PASI scores and 5 cc of blood was drawn for GGT, hs-CRP, and apo B examinations. A PASI score is a tool used to measure the severity and extent of psoriasis. PASI is an acronym for Psoriasis Area and Severity Index.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 33
• Est. completion date: December 30, 2022
• Est. primary completion date: December 30, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 60 Years

Eligibility

Inclusion Criteria:

• Clinical diagnosis of Psoriasis

Exclusion Criteria:

• Heart Failure

• Diabetes Mellitus

• Kidney Disease

Related Conditions & MeSH terms

• Psoriasis

Locations

Country	Name	City	State
Indonesia	Universitas Sebelas Maret Hospital	Sukoharjo	Central Java

Sponsors (1)

Lead Sponsor	Collaborator
Universitas Sebelas Maret

Country where clinical trial is conducted

Indonesia, 

References & Publications (2)

Pratama YS, Pradiptakirana R, Rachmah A, Prabowo NA. Autoimmune Thrombocytopenia in SLE and COVID-19. Eur J Case Rep Intern Med. 2021 Nov 3;8(11):002863. doi: 10.12890/2021_002863. eCollection 2021. — View Citation

Sholihah MM, Kusuma TRH, Hanif MI, Prabowo NA. Letter to the Editor on Type 1 diabetes onset triggered by COVID-19. Acta Diabetol. 2021 Sep;58(9):1283-1284. doi: 10.1007/s00592-021-01761-3. Epub 2021 Jun 28. No abstract available. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Gamma-Glutamyl Transferase	Gamma-Glutamyl Transferase was check in admission, reference range for adults is 5 to 40 U/L (units per liter)	only in admission
Primary	Apolipoprotein B	Apolipoprotein B (ApoB) is the primary apolipoprotein and is the carrier for the following lipids: chylomicrons, low-density lipoprotein ( LDL), very low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), and lipoprotein. Unit used in mg/dL	only in admission
Primary	High-sensitivity c-reactive protein	High-sensitivity C-reactive protein (hsCRP) is a marker of inflammation that predicts incident myocardial infarction, stroke, peripheral arterial disease, and sudden cardiac death. Unit used in mg/L	only in admission
Primary	PASI	A PASI (The Psoriasis Area and Severity Index) score can range from 0 to 72	only in admission