Psoriasis Clinical Trial
Official title:
Analysis and Correlation of Cathelicidin Expression in Skin and Saliva of Subjects With Atopic Dermatitis and Psoriasis
Cathelicidins are small proteins in the human body that protect against infection. The purpose of this study is to determine if the amount of cathelicidins and other small proteins found in saliva can predict the amount of these in the skin of people who have acute atopic dermatitis (AD) or psoriasis.
People with AD or psoriasis are very sensitive to skin infections and inflammations. A group
of small proteins known as cathelicidins are known to be responsible for immune defense
against such infections. People with AD or psoriasis seem to be missing these proteins from
their skin. The purpose of this study is to determine if the amount of cathelicidins and
other small proteins in saliva is a predictor for the amount found in the skin.
This is a single visit observational study. People with AD or psoriasis, as well as healthy
participants, are being recruited for this study. Participants will provide a detailed
medical history and undergo a physical examination. In addition, saliva and blood
collection, and skin punch biopsies will be performed.
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Observational Model: Case Control, Time Perspective: Prospective
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