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Psoriasis clinical trials

View clinical trials related to Psoriasis.

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NCT ID: NCT04614298 Withdrawn - Clinical trials for Moderate to Severe Plaque Psoriasis

A Phase 4 Study of Brodalumab (KHK4827) in Subjects With Moderate to Severe Plaque Psoriasis

Start date: January 2021
Phase: Phase 4
Study type: Interventional

The objective of this study is assessing the efficacy and safety of brodalumab in Chinese subjects with moderate to severe plaque psoriasis.

NCT ID: NCT04612699 Active, not recruiting - Clinical trials for Moderate-to-Severe Plaque Psoriasis

A Phase 2 Study of Jaktinib in Participants With Moderate to Severe Psoriasis

PSO
Start date: March 11, 2021
Phase: Phase 2
Study type: Interventional

This is study designed to investigate the efficacy and safety of Jaktinib in the treatment of participants with moderate to severe, chronic plaque psoriasis as assessed by the Psoriasis Area and Severity Index (PASI) score and routine safety assessments.

NCT ID: NCT04607980 Completed - Plaque Psoriasis Clinical Trials

A Study to Investigate ABP 654 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis

Start date: November 11, 2020
Phase: Phase 3
Study type: Interventional

The purpose of the study is to evaluate the efficacy, safety, and immunogenicity of ABP 654 compared with ustekinumab in participants with moderate to severe plaque psoriasis.

NCT ID: NCT04603027 Completed - Psoriasis Clinical Trials

A Phase 2 Study Investigating the Effect of EDP1815 in the Treatment of Mild to Moderate Plaque Psoriasis

Start date: September 21, 2020
Phase: Phase 2
Study type: Interventional

This Phase 2 study has been designed to investigate the clinical safety and efficacy of EDP1815 and to identify an optimal dose in subjects with mild to moderate psoriasis.

NCT ID: NCT04595409 Completed - Plaque Psoriasis Clinical Trials

A Double-blind Study to Compare the Efficacy, Safety, and Immunogenicity of the Proposed Biosimilar Ustekinumab FYB202 to Stelara® in Patients With Moderate-to-Severe Plaque Psoriasis

VESPUCCI
Start date: November 9, 2020
Phase: Phase 3
Study type: Interventional

This is a randomized, double-blind, multicenter study to evaluate the efficacy, safety, and immunogenicity of FYB202 compared to Stelara® in patients with Moderate-to-Severe Plaque Psoriasis.

NCT ID: NCT04594928 Completed - Plaque Psoriasis Clinical Trials

A Study Evaluating the Effects of GLPG3667 Given as an Oral Treatment for 4 Weeks in Adults With Moderate to Severe Plaque Psoriasis

Start date: October 19, 2020
Phase: Phase 1
Study type: Interventional

The purpose of this research study is to assess the safety, tolerability, efficacy, pharmacokinetics and pharmacodynamics of GLPG3667 in multiple daily oral doses in subjects with moderate to severe plaque psoriasis.

NCT ID: NCT04587362 Completed - Psoriasis Clinical Trials

The Diagnostic Ultrasound Enthesitis Tool (DUET) Study

DUET
Start date: March 17, 2021
Phase:
Study type: Observational

Psoriatic arthritis (PsA) is a type of joint disease that can lead to severe joint damage and disability within the first few years of the disease. This is why early detection and treatment of the disease is essential to prevent serious joint damage and improve long-term outcomes in these patients. However, there is currently no reliable way to tell the difference between PsA and other types of joint disease. This makes it difficult to detect PsA early. Enthesitis is an inflammation of the area where muscle tendons and ligaments attach to bones. Enthesitis is a key feature in PsA and can be easily detected using ultrasonography. The aim of this research study is to develop a system to evaluate enthesitis using ultrasonography, which can be used as an effective tool in the early detection of PsA. This will help in providing patients with early treatment to prevent further joint damage.

NCT ID: NCT04581044 Completed - Covid19 Clinical Trials

Impact of COVID-19 on Psoriasis Practice

Start date: September 17, 2020
Phase:
Study type: Observational

COVID-19 had a major impact on dermatology practice globally with special emphasis on chronic diseases e.g. psoriasis. The main objective of this work is to investigate the effect of COVID-19 pandemic on psoriasis management. This work is designed as a cross-sectional survey based on a questionnaire directed to Egyptian dermatologists.

NCT ID: NCT04580537 Completed - Nail Psoriasis Clinical Trials

Assessing the Efficacy of Image-guided Laser-assisted Enstilar® Delivery for Treatment of Psoriatic Nails

LAsED
Start date: October 2, 2020
Phase: Phase 2
Study type: Interventional

The trial is conducted to investigate the clinical efficacy of a combination product containing calcipotriol and betamethasone formulated as an aerosol foam (Enstilar ©) for the treatment of nail psoriasis in conjunction with physical pre-treatment using a fractionally ablative carbon dioxide laser (AFL). It is hypothesized, based on preclinical data and comparable clinical trials, that laser processing prior to topical administration will lead to increased drug distribution, and thereby increase the efficacy of Enstilar® in treating nail psoriasis.

NCT ID: NCT04572997 Completed - Clinical trials for Palmoplantar Pustulosis

Apremilast in Patients With Moderate to Severe Palmoplantar Pustulosis (PPP) (APLANTUS)

APLANTUS
Start date: November 29, 2018
Phase: Phase 2
Study type: Interventional

Multicenter, open-label, single-arm, phase II, pilot study. The screening period was up to 4 weeks and treatment took place over 20 weeks per patient. Five visits per patient were performed including: Visit 1 at week -4 to -1 (screening), Visit 2 at week 0 (baseline), Visit 3 at week 4, Visit 4 at week 12, and Visit 5 at week 20 (end of study). There was no follow-up period.