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Psoriasis clinical trials

View clinical trials related to Psoriasis.

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NCT ID: NCT00267969 Completed - Psoriasis Clinical Trials

A Study of Safety and Effectiveness of Ustekinumab (CNTO 1275) in Patients With Moderate to Severe Plaque-type Psoriasis

PHOENIX1
Start date: December 2005
Phase: Phase 3
Study type: Interventional

The primary purpose of this study is to evaluate the effectiveness and safety of ustekinumab (CNTO 1275) in the treatment of patients with moderate to severe plaque psoriasis.

NCT ID: NCT00263718 Completed - Psoriasis Vulgaris Clinical Trials

Efficacy and Safety of Calcipotriol Plus Betamethasone Dipropionate Gel in Psoriasis Vulgaris

Start date: December 2005
Phase: Phase 2
Study type: Interventional

The objective of the study is to compare the use of calcipotriol plus betamethasone dipropionate gel with betamethasone dipropionate in the gel vehicle, calcipotriol in the gel vehicle and the gel vehicle alone when used in patients with psoriasis vulgaris on the trunk and/or limbs. Patients will be treated once daily for up to 8 weeks. The primary response criterion is the number of patients with controlled disease at week 8.

NCT ID: NCT00261976 Completed - Psoriasis Clinical Trials

A Long-term Safety Study of Infliximab (Remicade)

Start date: February 2002
Phase: Phase 4
Study type: Observational

This is a study evaluating the long-term safety of infliximab (Remicade)

NCT ID: NCT00258713 Completed - Psoriasis Clinical Trials

A 36-Week Extension to Protocol ISA04-03

SPIRIT
Start date: September 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the safety and efficacy of voclosporin in patients with plaque psoriasis.

NCT ID: NCT00256139 Completed - Clinical trials for Moderate to Severe Psoriasis

CLEAR Study: Clinical Experience Acquired With Raptiva Study

Start date: March 2003
Phase: Phase 3
Study type: Interventional

A multicentre, randomised, double blind, placebo controlled phase III study of subcutaneously administered Raptiva in the treatment of patients with moderate to severe psoriasis

NCT ID: NCT00254982 Completed - Psoriasis Clinical Trials

Infliximab in High Need Versus Low Need Psoriasis Patients: The IHELP Study (Study P04320)(COMPLETED)

Start date: August 2005
Phase: Phase 3
Study type: Interventional

This is an open-label, multicenter, parallel-group comparison study of the efficacy, safety, and tolerability of infliximab therapy in adult patients suffering from chronic plaque psoriasis (psoriasis vulgaris). Patients will be assigned to GROUP I ("high need") or GROUP II ("low-need") by the investigator according to their previous psoriasis treatment.

NCT ID: NCT00251641 Completed - Psoriasis Clinical Trials

The Effects of Infliximab Versus Methotrexate in the Treatment of Moderate to Severe Psoriasis (Study P04271AM2)(COMPLETED)

Start date: September 2005
Phase: Phase 3
Study type: Interventional

This is a Phase 3b, randomized, parallel-group, multicenter, active-controlled, open-label study of the efficacy and safety of infliximab compared with methotrexate (MTX) in the treatment of moderate to severe psoriasis in adults who were diagnosed with moderate to severe plaque-type psoriasis for at least 6 months prior to screening (subjects with concurrent psoriatic arthritis may also be enrolled).

NCT ID: NCT00249808 Completed - Psoriasis Clinical Trials

A Study of Efalizumab in Participants With Moderate to Severe Chronic Psoriasis Who Have Failed, Have a Contraindication to, or Are Intolerant of Other Systemic Therapies

Start date: December 13, 2004
Phase: Phase 4
Study type: Interventional

This is a Phase IIIb/IV, open label, multicentre study of efalizumab (anti cluster of differentiation [CD] 11a recombinant human monoclonal antibody) in participants with moderate to severe plaque psoriasis who have failed to respond to, have a contraindication to, or are intolerant to other systemic therapies including ciclosporin, methotrexate, and psoralen and ultraviolet A phototherapy (PUVA).

NCT ID: NCT00248456 Completed - Psoriasis Vulgaris Clinical Trials

Efficacy and Safety of Calcipotriol Plus Betamethasone Dipropionate Ointment in Patients With Psoriasis Vulgaris

Start date: October 2005
Phase: Phase 4
Study type: Interventional

This study will evaluate the efficacy and safety of calcipotriol plus betamethasone dipropionate ointment compared with calcipotriol ointment in the treatment of patients with psoriasis vulgaris for a duration of 4 weeks. The study will focus on the percentage change of the psoriasis area and severity index (PASI) from baseline to the end of week 4.

NCT ID: NCT00245765 Completed - Clinical trials for Chronic Plaque Psoriasis

Efficacy Study of CDP870 in Subjects With Chronic Plaque Psoriasis Who Are Candidate for Systemic Therapy and/or Phototherapy/Photochemotherapy

Start date: October 2005
Phase: Phase 2
Study type: Interventional

A study to assess the safety and efficacy of 2 different doses of CDP870 versus placebo, administered during 12 weeks, to patients suffering from moderate to severe chronic plaque psoriasis, extended by a 12 to 24 week follow-up.