Ultraviolet Radiation Forecasting Based Heliotherapy For Psoriasis in Bangkok, Thailand

Psoriasis Vulgaris Clinical Trial

Official title:

The Study of Efficacy and Safety of UV Forecasting Based Heliotherapy For Psoriasis in Bangkok, Thailand: A Split-side Pilot Study

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT04740983
• Other study ID #: 500/62
• Status: Not yet recruiting
• Phase: N/A
• Start date: March 15, 2021
• Est. completion date: December 31, 2021

Study information

• Verified date: February 2021
• Source: Chulalongkorn University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Due to limited number of phototherapy centres and shortage of qualified phototherapy practitioners, heliotherapy has become a promising treatment alternative in Thailand where patients effortlessly receive supervised sun-bathing treatments from their homes whenever they are convenient. We used newly designed deep neural network UV forecasting model developed by using our 10 year-retrospective Solar UV irradiance (280-400 nm) retrieved from a ground based platform at Atmosperic laboratory, Silpakorn University, Nakhon Pathom, Thailand (13.82N 100.04E, 30 m above mean sea level). This model achieved a next-day forecast error of less than 12% which has been the most accurate prediction to date. We designed our 10week heliotherapy regimen based on the predicted anti psoriasis effective irradiance values. We studied efficacy and safety of the 12-week heliotherapy regimen for psoriasis on only ruled acceptable clear sky days in Bangkok, Thailand

Description:

We studied efficacy and safety of the 16-week heliotherapy regimen for psoriasis on only ruled acceptable clear sky days in Bangkok, Thailand

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 20
• Est. completion date: December 31, 2021
• Est. primary completion date: August 30, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• A psoriasis patient who indicate to have phototherapy and have lesional plagues systemically either on the front-back or left-right.

• A participant is based in Bangkok

• A participant is capable to understand and learn how to use our in-house assembled UV metre and web-based heliotherapy platform.

Exclusion Criteria:

• A participant has any sun-sensitive conditions including photo-aggravated photodermatoses and on photosentisitive drug treatments.

• Breast-feeding, pregnant individuals.

Related Conditions & MeSH terms

• Psoriasis
• Psoriasis Vulgaris

Intervention

Other:
• Heliotherapy (a sole sun-bathing)
16-week heliotherapy regimen based on the predicted anti psoriasis effective irradiance values.

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
Chulalongkorn University	King Chulalongkorn Memorial Hospital

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Changes of Targeted PASI score	PASI score for targeted plagues will be evaluated by two independent dermatologists (EB, PA) from standard digital photographs.	16 weeks
Secondary	Incidence of possible acute side effects after sun bathing	Potential acute effects of the exposure of full-spectrum solar radiation	16 weeks