Psoriasis Palm & Soles Clinical Trial
Official title:
Treatment of Palmoplantar Psoriasis With Low Doses Interferential Current
Interferential current has shown promising results for treating psoriasis with a good
tolerance. Prospective randomized studies versus placebo are required to confirm the
interest of such an approach.
The Main objective is to assess the efficacy of interferential current for treating
palmoplantar psoriasis.
Secondary objectives is to assess the subjective efficacy by the patients, the efficacy on
the nails, to study the potential side effects.
Interferential current has shown promising results for treating psoriasis with a good
tolerance. Prospective randomized studies versus placebo are required to confirm the
interest of such an approach.
Main objective To assess the efficacy of interferential current for treating palmoplantar
psoriasis.
Secondary objectives To assess the subjective efficacy by the patients, the efficacy on the
nails, to study the potential side effects.
Patients Patients from 18 to 90 year-old with psoriasis on the hands and/or feet. Length of
the study: 12 months Methods Monocentric randomized comparative study versus
placebo.Intervention V0 : Selection: Information of the patient, control of inclusion and
non inclusion criteria.
V1 : Control of inclusion and non inclusion criteria (treatment against psoriasis have to be
discontinued for at least 3 weeks and 3 months for anti-IL12/23). Clinical scores and
photographs. Explanation of the functioning of the device, then the treatment is followed at
home, twice a day 5 minutes. 10% salicylic acid ointment will be applied after each session.
V2 : End of the treatment (12 weeks after V1). Clinical scores and photographs. V3 : End of
the follow-up (24 weeks after V1). Clinical scores and photographs.
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Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment