Effect of Anesthesia on Optic Nerve Sheath Diameter in Patients Undergoing Robot-assisted Laparoscopic Prostatectomy

Prostate Cancer Clinical Trial

Official title:

Effect of Inhalation Anesthesia With Sevoflurane and Total Intravenous Anesthesia With Propofol on Optic Nerve Sheath Diameter in Patients Undergoing Robot-assisted Laparoscopic Prostatectomy

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03271502
• Other study ID #: 2017-1011
• Status: Completed
• Phase: N/A
• First received: August 31, 2017
• Last updated: October 25, 2017
• Start date: September 4, 2017
• Est. completion date: October 1, 2017

Study information

• Verified date: October 2017
• Source: Asan Medical Center
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study was to evaluate the difference between the optic nerve sheath diameter measured during total intravenous anesthesia and the optic nerve sheath diameter measured during inhalation anesthesia in patients undergoing robot-assisted laparoscopic prostatectomy.

Description:

The purpose of this study was to evaluate the difference between the optic nerve sheath diameter measured during total intravenous anesthesia with propofol and remifentanil and the optic nerve sheath diameter measured during inhalation anesthesia with sevoflurane and remifentanil in patients undergoing robot-assisted laparoscopic prostatectomy.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 36
• Est. completion date: October 1, 2017
• Est. primary completion date: September 26, 2017
• Accepts healthy volunteers: No
• Gender: Male
• Age group: 20 Years to 79 Years

Eligibility

Inclusion Criteria:

Patients who have undergone a robot-assisted laparoscopic prostatectomy with a prostate cancer and who are 20 years of age or older and under 80 years of age and who agree to participate in this study.

Exclusion Criteria:

Patients with a history of cerebral hemorrhage or cerebral infarction, Patients < 20 years of age, Patients = 80 years of age, Patients with unexpected hemodynamic instability during surgery, Failure to measure optic nerve sheath diameter.

Related Conditions & MeSH terms

• Prostate Cancer

Intervention

Procedure:
• Total intravenous anesthesia
Total intravenous anesthesia with propofol and remifentanil
• Inhalation anesthesia
Inhalation anesthesia with sevoflurane and remifentanil

Locations

Country	Name	City	State
Korea, Republic of	Asan Medical Center	Seoul

Sponsors (1)

Lead Sponsor	Collaborator
Asan Medical Center

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Difference in optic nerve sheath diameter	Difference between the optic nerve sheath diameter measured during total intravenous anesthesia and the optic nerve sheath diameter measured during inhalation anesthesia	60 minutes after pneumoperitoneum and steep Trendelenburg position
Secondary	Difference in optic nerve sheath diameter	Difference between the optic nerve sheath diameter measured during total intravenous anesthesia and the optic nerve sheath diameter measured during inhalation anesthesia	30 minutes after pneumoperitoneum and steep Trendelenburg position
Secondary	Difference in optic nerve sheath diameter	Difference between the optic nerve sheath diameter measured during total intravenous anesthesia and the optic nerve sheath diameter measured during inhalation anesthesia	5 minutes after pneumoperitoneum and steep Trendelenburg position