Proliferative Vasculopathy Clinical Trial
Official title:
Clinical and Molecular Characterization of Cerebral Proliferative Vasculopathy
As principal objective, the study aims to:
1. Describe the spectrum and evaluate the frequency of angiodysplasia of the nevrax;
2. Establish the physiopathological basis of Fowler's syndrome;
3. Identify FLVCR2 partners and the signaling pathways involved;
4. Test new candidate genes: GPR124 and possible partners of FLVCR2.
As second objective, the study aims to:
- perform phenotype / genotype correlation if necessary;
- and propose a prenatal diagnosis in families with identified mutations.
n/a