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Prolapse clinical trials

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NCT ID: NCT00810745 Completed - Rectal Prolapse Clinical Trials

What Benefit With a New Stapler Device in the Surgical Treatment of Obstructed Defecation?

Start date: January 2006
Phase: Phase 4
Study type: Interventional

This randomized study was designed to compare the 2 year clinical and functional results with the STARR procedure using a new curved cutter stapler or the same operation done with 2 traditional circular staplers.

NCT ID: NCT00803335 Completed - Clinical trials for Pelvic Organ Prolapse

The Effects of Local Vaginal Estrogen in Postmenopausal Women With Pelvic Organ Prolapse

Start date: December 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to find out how long it takes the vagina to respond to hormonal vaginal cream in women with pelvic organ prolapse (bulge in the vagina). It also will address the appropriate amount to use prior to vaginal repair of pelvic organ prolapse.

NCT ID: NCT00799565 Completed - Clinical trials for Mitral Valve Prolapse

Mitral Valve Prolapse (MVP) - France Study

MVP-France
Start date: December 2008
Phase: N/A
Study type: Interventional

This prospective nation-wide (France) study aims to search for susceptibility genes in MVP using a genome wide analysis and comparing results obtained in 1000 patients with MVP and 1000 non-MVP subjects.

NCT ID: NCT00784602 Terminated - Genital Prolapse Clinical Trials

Observing Pelvic Organ Prolapse Symptoms And Treatment Outcomes

Start date: October 29, 2008
Phase: N/A
Study type: Observational

To prospectively observe the outcomes of surgical prolapse treatment in terms of urinary, bowel, and sexual function, quality of life, patient satisfaction, cost, and achieving patient determined treatment goals.

NCT ID: NCT00774215 Completed - Clinical trials for Pelvic Organ Prolapse

Evaluation of the Avaulta Procedure for the Correction of Pelvic Organ Prolapse - Results at 1 Year

Start date: October 2007
Phase: N/A
Study type: Observational

This study is a 1 year review of all patients who had surgery to correct pelvic organ prolapse (i.e. cystocele, rectocele, enterocele) using the Avaulta synthetic mesh kit.

NCT ID: NCT00771225 Active, not recruiting - Genital Prolapse Clinical Trials

National,Multicentric Randomised Study of the Correction of Genital Prolapse With Fascial Repair or Mesh-Prolift

Start date: November 2008
Phase: Phase 4
Study type: Interventional

180 women with genital prolapse will be submitted to genital prolapse surgical correction, half of them with human fascia, and the other half with Prolift.

NCT ID: NCT00769054 Completed - Vaginal Prolapse Clinical Trials

Local Infiltration Analgesia With Ropivacaine in Posterior Vaginal Wall Prolapse:a Randomized, Double-Blind Study

Start date: October 2008
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare systematic local infiltration with ropivacaine or placebo in patients undergoing repair of posterior vaginal wall prolapse. The hypothesis is that LIA technique is opioid-sparing and a better postoperative treatment.

NCT ID: NCT00747370 Completed - Clinical trials for Stress Urinary Incontinence

Dynamic MRI of the Behaviour of Female Pelvic Floor

Start date: January 2002
Phase: Phase 0
Study type: Interventional

The purpose of this study was to test the suitability of dynamic magnetic resonance imaging for the pelvic floor floor, bladder neck and urethra in healthy volunteers, in stress incontinent patient and in women with genital prolapse.

NCT ID: NCT00714155 Completed - Clinical trials for Pelvic Organ Prolapse

Outcomes and Patient Satisfaction After Colpocleisis for Pelvic Organ Prolapse

Start date: July 2006
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate the long-term success rate of the colpocleisis procedure and its effect on quality of life in women who have this surgery. We want to see if women who have this surgery have problems with recurrent pelvic organ prolapse, urinary incontinence, or bowel problems after the surgery. We also want to see how the surgery affects women's sexuality.

NCT ID: NCT00697489 Withdrawn - Clinical trials for Pelvic Organ Prolapse

Treatment of Urinary Stress Incontinence During or Following Correction of Pelvic Organ Prolapse

Start date: June 2008
Phase: Phase 4
Study type: Interventional

The incidence of pelvic organ prolapse (POP) in parous women is estimated over 50%. A variety of urinary, bowel and sexual symptoms may be associated with POP. Moreover, a proportion of women who underwent a surgical correction of POP may occur post-surgical urinary incontinence and, thus, if this last presents as genuine stress-type or mixed-type, a second surgical intervention may be required. At this proposal, with the aim to reduce the incidence of postoperative urinary incontinence, the addition of a preventive continence procedure to a POP repair intervention has been widely proposed, but the potential benefits needs to be balanced against potential disadvantages. Based on these considerations, the aim of this trial will be to compare two different surgical strategies for women with POP without urinary stress incontinence. Specifically, the efficacy to associate and to follow a preventive continence procedure to the correction of POP will be compared.