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Prolapse clinical trials

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NCT ID: NCT00937430 Completed - Clinical trials for Pelvic Organ Prolapse

Bowel Preparation and Pelvic Organ Prolapse Surgery

Start date: March 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to find out if performing a bowel preparation prior to pelvic organ prolapse surgery has any effect on the return of bowel function after surgery.

NCT ID: NCT00928239 Recruiting - Clinical trials for Vaginal Vault Prolapse

Laparoscopic Sacropexy: Comparison of Mesh Attachment

MeshPlace
Start date: June 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to compare postoperative complications and outcome two different attachment sites of the dorsal mesh support in laparoscopic sacropexy.

NCT ID: NCT00918099 Recruiting - Vaginal Prolapse Clinical Trials

The Use of Avaulta for Anterior Repair

Start date: October 2008
Phase: N/A
Study type: Interventional

Summary: Vaginal prolapse is a well-known disease and is observed in approximately 11% of all postmenopausal women and tending to increase with age. Consequently, many surgical procedures have been developed in order to ensure sufficient support for the bladder, rectum or vaginal vault depending on the site of the defect. However, many procedures are associated with a high recurrence rate up to 40 % even within one to two years after the surgical procedure. Due to the high recurrence rate new methods include the use of mesh, either biologically or synthetic. The latter is a permanent implant and therefore theoretically may result in a long-lasting anatomically correct position of the prolapse. Although the recurrence rate may be lower using a mesh such surgical procedures may be associated with adverse events such as erosions of the vaginal mucosa. Others have observed shrinkage of the vaginal mucosa. However, in these studies large prolene mesh have been used. In contrast the recurrence rate is lowered up to 25%. The above-mentioned advantage of synthetic mesh is however, mostly based on few non-randomised studies. The investigators therefore find it of importance to evaluate whether a surgical procedure using a mesh implant is superior to conventional surgical techniques. The present study is a clinical controlled study where patients with anterior vaginal prolapse are randomised to either a mesh technique or a standard anterior procedure. The present study includes only two more visits at the outpatient clinic after the surgical procedure. Furthermore the patients have to fulfil questionnaires regarding urinary and faecal leakage and sexual habits. Any participation in the study is totally voluntary and the patient may at any time withdraw herself. In any case the patient will receive the investigators' standard treatment.

NCT ID: NCT00886223 Recruiting - Clinical trials for Vaginal Vault Prolapse

Laparoscopic Sacropexy With Robot-Assisted Surgical System

RobPex
Start date: April 2009
Phase: N/A
Study type: Interventional

The aim of the study is to evaluate safety and outcome of robot-assisted laparoscopic sacropexy regarding perioperative data, objective anatomical results and postoperative quality of life.

NCT ID: NCT00860912 Completed - Clinical trials for Pelvic Organ Prolapse

Veritas Collagen Matrix Cystocele Repair Study - Postmarketing

Start date: December 2001
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the Veritas Collagen Matrix in treating female patients with documented occurence of Pelvic Organ Prolapse as evidenced by a cystocele.

NCT ID: NCT00859417 Completed - Anterior Prolapse Clinical Trials

Study Evaluating the Effectiveness of the Use of Prosthesis With Trans-Obturator Way for the Correction of Anterior Prolapse

Start date: September 2008
Phase: N/A
Study type: Interventional

The classical surgical treatment of an anterior prolapse is the use of autologous tissue. In front of the high rate of recurrences with this technique, the use of synthetic prosthesis made their appearance. But the drawback of the use of prosthesis is their tolerability. The system Perigee®, a prosthetic kit by trans-obturator way, was designed to obtain high efficiency in the correction of the prolapse while reducing the risk of complications. The lack of prospective and randomized studies makes difficult to assess the interest. The investigators, therefore, have put in place a randomized prospective study seeking the evaluation of the system Perigee® compared to the conventional surgical technique.

NCT ID: NCT00836680 Recruiting - Clinical trials for Internal Rectal Prolapse

Clinical Study for the Evaluation of the Efficiency of a Device for the Diagnosis of an Internal Rectal Prolapse, a Pelvic Floor Ptosis and for the Determination of an Internal Hernia Into the Douglas Pouch

Start date: January 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if the device is supplying sufficient diagnosis results of an internal rectal prolapse, of a pelvic floor ptosis and for the determination of an interal hernia into the Douglas pouch, as well as to determine the technical success of using the device at the patient.

NCT ID: NCT00833001 Completed - Cystocele Clinical Trials

Clinical Performance of the GYNECARE PROLIFT + M* Pelvic Floor Repair System as a Device for Pelvic Organ Prolapse

Start date: April 2008
Phase: Phase 2/Phase 3
Study type: Observational

The purpose of this study is to evaluate the clinical performance of the PROLIFT system with a new lighter-weight mesh in repair of vaginal prolapse.

NCT ID: NCT00827645 Withdrawn - Incontinence Clinical Trials

Uterine Artery Embolization and Pelvic Floor Symptoms

Start date: January 1, 2009
Phase:
Study type: Observational

The objective of this study is to determine whether women who are already receiving treatment for their fibroids (ie. UAE) demonstrate improvement in urinary symptoms and sexual dysfunction as well.

NCT ID: NCT00827528 Completed - Clinical trials for Pelvic Organ Prolapse

SIS Graft and Traditional Repair in Vaginal Wall Prolapse

Start date: August 2006
Phase: Phase 4
Study type: Interventional

The objective of this study is to evaluate surgical treatment of anterior vaginal wall prolapse using the sis graft or traditional repair. This a randomized and prospective study. Clinical patterns that will be evaluated: anatomic results of surgery; impact of surgery in quality of life using the Pelvic Organ Prolapse Questionnaire (P-QoL), sexual function with FSFI and possible complications.